Evidence map›Paper›PMID 34745728›Full record

ArticleBiomedical optics express2021

Imaging the dynamics of individual processes of microglia in the living retina

Aby Joseph, Derek Power, Jesse Schallek

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. 100-degree Non-Contact Retinal Imaging in Mice Using a Multimodal Vis-OCT and SLO System.IEEE photonics technology letters : a publication of the IEEE Laser and Electro-optics Society · 2026
    Article
  2. Review
  3. Eppur si muove: the dynamic brain pericyte.Fluids and barriers of the CNS · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Non-invasiveFrontiers in cellular neuroscience · 2024
    Review
  12. The RBPMSiScience · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Schizophrenia in Translation: Why the Eye?Schizophrenia bulletin · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aby JosephThe Institute of Optics, University of Rochester, Rochester, NY 14620, USA.ORCID https://orcid.org/0000-0001-8143-801X
Derek PowerCenter for Visual Science, University of Rochester, Rochester, NY 14627, USA.
Jesse SchallekCenter for Visual Science, University of Rochester, Rochester, NY 14627, USA.
University of Rochester · US

Funding

VISUAL SCIENCE RESEARCH CTR SUPPORTP30EY001319 · NEI · UNIVERSITY OF ROCHESTER · PI MICHELE RUCCI · 1985 to 2026
$17.5M
Non-invasive, living histology of capillary structure and single cell blood flow in mouse model of diabetic retinopathyR01EY028293 · NEI · UNIVERSITY OF ROCHESTER · PI SCHALLEK, JESSE BARRETT · 2017 to 2025
$4.2M
NEI NIH HHS P30 EY001319NEI NIH HHS R01 EY028293
6 · The paper itself

Abstract

Microglia are an essential population of resident immune cells in the central nervous system (CNS) and retina. These microscopic cells possess sub-cellular processes that make them challenging to image due to limited resolution and contrast. The baseline behavior of microglial processes in the living retina has been poorly characterized, and yet are essential to understanding how these cells respond under conditions of health, development, stress and disease. Here we use

Identifiers

PMID34745728
PMCPMC8547988
OpenAlexW3196807647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.