Evidence map›Paper›PMID 34745693›Full record

ArticleChina CDC weekly2021

Genetic Characterization of Two Human Cases Infected with the Avian Influenza A (H5N6) Viruses - Guangxi Zhuang Autonomous Region, China, 2021.

Fuyin Bi, Lili Jiang, Lihua Huang, Jingguang Wei, Xiaowen Pan, Yu Ju, Jianjun Mo, Minmei Chen, Ning Kang, Yi Tan and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in China CDC weekly, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Avian influenza overview September - December 2021.EFSA journal. European Food Safety Authority · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fuyin BiGuangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Control and Prevention, Nanning, Guangxi Zhuang Autonomous Region, China.
Lili JiangGuilin Center for Disease Control and Prevention, Guilin, Guangxi Zhuang Autonomous Region, China.
Lihua HuangHechi Center for Disease Control and Prevention, Hechi, Guangxi Zhuang Autonomous Region, China.
Jingguang WeiHechi Center for Disease Control and Prevention, Hechi, Guangxi Zhuang Autonomous Region, China.
Xiaowen PanGuilin Center for Disease Control and Prevention, Guilin, Guangxi Zhuang Autonomous Region, China.
Yu JuGuangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Control and Prevention, Nanning, Guangxi Zhuang Autonomous Region, China.
Jianjun MoGuangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Control and Prevention, Nanning, Guangxi Zhuang Autonomous Region, China.
Minmei ChenGuangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Control and Prevention, Nanning, Guangxi Zhuang Autonomous Region, China.
Ning KangGuangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Control and Prevention, Nanning, Guangxi Zhuang Autonomous Region, China.
Yi TanGuangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Control and Prevention, Nanning, Guangxi Zhuang Autonomous Region, China.
Yonghong LiGuangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Control and Prevention, Nanning, Guangxi Zhuang Autonomous Region, China.
Jing WangGuangxi Key Laboratory of Major Infectious Disease Prevention and Control and Biosafety Emergency Response, Guangxi Center for Disease Control and Prevention, Nanning, Guangxi Zhuang Autonomous Region, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

WHAT IS KNOWN ABOUT THIS TOPIC?: H5N6 has replaced H5N1 as a dominant avian influenza virus (AIV) subtype in southern China. The increasing genetic diversity and geographical distribution of H5N6 pose a serious threat to the poultry industry and human health. WHAT IS ADDED BY THIS REPORT?: A total of 2 cases of H5N6 that occurred from February 2021 to July 2021 in Guangxi, China were reported in this study. Phylogenetic analysis of gene was constructed, and some mutations of HA gene, PB2 gene, PA gene, M1 gene, NS1 gene, the receptor-binding site were detected. The evolutionary origins of the internal genes were different. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: As a multi-source reassortant virus, the H5N6 highly pathogenic AIV is continuously evolving. There is an urgent need to strengthen the surveillance of drug-resistant strains and novel variants.

Indexed as

avian influenza virusH5N6human infectionPhylogenetic analysis

Identifiers

PMID34745693
PMCPMC8563334

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.