Evidence map›Paper›PMID 34745599›Full record

ReviewAnnals of medicine and surgery (2012)2021

The role of debridement in wound bed preparation in chronic wound: A narrative review.

Deena Clare Thomas, Chong Li Tsu, Rose A Nain, Norkiah Arsat, Soong Shui Fun, Nik Amin Sahid Nik Lah

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07732036 (The Effectiveness and Acceptability of Inhalation Aromatherapy for Patients Undergoing Conservative Sharp Wound Debridement), which is not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07732036 narecruitingnot on this mapstarted 2026, after this paper: background citation

The Effectiveness and Acceptability of Inhalation Aromatherapy for Patients Undergoing Conservative Sharp Wound Debridement: A Pilot Randomized Controlled Trial

TypeinterventionalSponsorSingapore General HospitalRan2026 to 2028Enrolled40ConditionsAromatherapyArmsInhalation Aromatherapy
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Exploring New Horizons in Wound Healing: A Comprehensive Analysis.Recent advances in inflammation & allergy drug discovery · 2026
    Review
  9. Article
  10. [Comprehensive management of tophaceous wound].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Review
  11. Review
  12. What's New in Wound Healing: Treatment Advances and Microbial Insights.American journal of clinical dermatology · 2025
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Trends in the Treatment of Chronic Wounds.Current medicinal chemistry · 2025
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Deena Clare ThomasDepartment of Nursing, Faculty of Medicine and Health Sciences Universiti Malaysia Sabah, UMS Road, 88400, Kota Kinabalu, Sabah, Malaysia.
Chong Li TsuDepartment of Nursing, Faculty of Medicine and Health Sciences Universiti Malaysia Sabah, UMS Road, 88400, Kota Kinabalu, Sabah, Malaysia.
Rose A NainDepartment of Nursing, Faculty of Medicine and Health Sciences Universiti Malaysia Sabah, UMS Road, 88400, Kota Kinabalu, Sabah, Malaysia.
Norkiah ArsatDepartment of Nursing, Faculty of Medicine and Health Sciences Universiti Malaysia Sabah, UMS Road, 88400, Kota Kinabalu, Sabah, Malaysia.
Soong Shui FunDepartment of Nursing, Faculty of Medicine and Health Sciences Universiti Malaysia Sabah, UMS Road, 88400, Kota Kinabalu, Sabah, Malaysia.
Nik Amin Sahid Nik LahDepartment of Surgery, Faculty of Medicine and Health Sciences Universiti Malaysia Sabah, UMS Road, 88400, Kota Kinabalu, Sabah, Malaysia.
Universiti of Malaysia Sabah · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo provide an overview of the types of wound debridement and update the available scientific consensus on the effect of wound debridement.

methodsThe articles were searched through CINAHL, PubMed, Cochrane Library, and Medline database for relevant articles on all types of wound debridement. Articles included were all systematic review on the effectiveness of wound debridement-related outcome, published within the year 2017 until Aug 2021, in English.

resultsA total of seven scientific articles had been selected for review out of 318 screened. The authors reviewed a total of 318 titles and abstracts related to wound debridement effectiveness. Seven articles that were selected were narratively reviewed by two authors. The findings of the review were organized into autolytic, enzymatic, sharp, surgical, biological, and mechanical debridement methods and includes the advantages and disadvantages of each. The author further explored on the role of wound debridement according to wound bed preparation model. Articles were synthesized and organized based on the authors, year, total studies included in the systematic review, study range of year, total sample, debridement method, wound types, and findings.

conclusionMaggot debridement therapy showed a consistent finding in terms of effectiveness in debriding chronic wounds. The newer debridement method includes hydro-surgery, low-frequency ultrasonic and enzymatic collagenase debridement were getting more attention due to faster wound bed preparation and less painful. However, these newer method of debridements showed inconclusive findings and the patient safety was not clearly defined. A higher level of review is warranted in the future study.

Indexed as

Chronic woundDebridementSurgicalWound bed preparationWound healing

Identifiers

PMID34745599
PMCPMC8554455
OpenAlexW3206456094

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.