Methods to measure calcitonin receptor activity, up-regulated in cell stress, apoptosis and autophagy.

Peter Wookey, Pragya Gupta, Lucas Bittencourt, Shane Cheung, David Hare, Sebastian Furness

Open access · goldAbstract readReview

In one paragraph

Review in F1000Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 47% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

Network topology-directed design of molecular CPU for cell-like dynamic information processing.Science advances · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Peter WookeyMedicine, University of Melbourne, Heidelberg, Victoria, 3084, Australia.ORCID 0000-0002-3937-1621

Pragya GuptaMedicine, University of Melbourne, Heidelberg, Victoria, 3084, Australia.ORCID 0000-0001-8617-0817

Lucas BittencourtMedicine, University of Melbourne, Heidelberg, Victoria, 3084, Australia.

Shane CheungBOMP, University of Melbourne, Parkville, Victoria, 3052, Australia.

David HareMedicine, University of Melbourne, Heidelberg, Victoria, 3084, Australia.

Sebastian FurnessDrug Discovery Biology and Department of Pharmacology, Monash University, Parkville, Victoria, 3052, Australia.

The University of Melbourne · AUThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expression of the calcitonin receptor (CT Receptor) is widespread throughout the life cycle of mammals and in many diseases, and in these contexts the functions of the common isoforms is largely unknown. The relatively recent development of anti-CT Receptor antibodies that bind separate epitopes on the CT

Indexed as

AutophagyReceptors, CalcitoninAnimalsApoptosisLysosomesSignal TransductionReceptors, Calcitoninantibodyantibody conjugateapoptosisautophagycalcitonin receptor isoformcell stresshigh content screeningnanopore sequencingquantitative PCR

Identifiers

PMID34745567

DOI10.12688/f1000research.72845.1

PMCPMC8543166

OpenAlexW3202734627

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.