Evidence map›Paper›PMID 34745416›Full record

ArticleOxidative medicine and cellular longevity2021

Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways.

Ruoyun Wu, Tunyu Jian, Xiaoqin Ding, Han Lv, Xiuhua Meng, Bingru Ren, Jing Li, Jian Chen, Weilin Li

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. The beneficial Effects ofCurrent diabetes reviews · 2026
    Article
  3. Review
  4. Review
  5. Role of TRP Channels in Metabolism-Related Diseases.International journal of molecular sciences · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Terpenoid-Rich Extract ofAntioxidants (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ruoyun WuInstitute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China.ORCID https://orcid.org/0000-0003-2431-2423
Tunyu JianInstitute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China.ORCID https://orcid.org/0000-0002-9814-500X
Xiaoqin DingInstitute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China.ORCID https://orcid.org/0000-0002-9365-6396
Han LvInstitute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China.ORCID https://orcid.org/0000-0003-4452-4351
Xiuhua MengInstitute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China.ORCID https://orcid.org/0000-0002-2249-3649
Bingru RenInstitute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China.ORCID https://orcid.org/0000-0003-1398-4953
Jing LiDepartment of Food Science and Technology, College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing 210037, China.ORCID https://orcid.org/0000-0002-2169-1512
Jian ChenInstitute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China.ORCID https://orcid.org/0000-0003-0686-833X
Weilin LiCo-Innovation Center for Sustainable Forestry in Southern China, Forestry College, Nanjing Forestry University, Nanjing 210037, China.
Chinese Academy of Sciences · CNNanjing Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loquat (

Indexed as

Diet, High-FatInsulin ResistanceAnimalsEriobotryaGene Expression RegulationGlucose Transporter Type 4GlycosidesHyperglycemiaHyperlipidemiasInsulin Receptor Substrate ProteinsMaleMiceMice, Inbred C57BLNF-E2-Related Factor 2Plant ExtractsPlant LeavesGlucose Transporter Type 4GlycosidesInsulin Receptor Substrate ProteinsIrs1 protein, mouseNfe2l2 protein, mouseNF-E2-Related Factor 2Plant ExtractsSesquiterpenesSirt6 protein, mouseSirtuinsSlc2a4 protein, mouseTRPV1 protein, mouseTRPV Cation Channels

Identifiers

PMID34745416
PMCPMC8566052
OpenAlexW3209713825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.