Evidence map›Paper›PMID 34745325›Full record

ArticleComputational and mathematical methods in medicine2021

The Clinical Efficacy of Clopidogrel Bisulfate Tablets Combined with Olmesartan Medoxomil for Ischemic Stroke with Hypertension and the Effect of Angiotensin II Type 1 Receptor Level on Prognosis.

Jia Yu, Wei Fang, Xing Guo, Haiyang Jiang, Peng Sun, Yufeng Liu, Xin Jin

Open access · hybridAbstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jia Yu *Department of Neurosurgery, Tangdu Hospital, Air Force Military Medical University, Xi'an, 710038, China.ORCID https://orcid.org/0000-0001-9352-1363
Wei Fang *Department of Neurosurgery, Tangdu Hospital, Air Force Military Medical University, Xi'an, 710038, China.ORCID https://orcid.org/0000-0002-3695-8187
Xing GuoDepartment of Neurosurgery, Tangdu Hospital, Air Force Military Medical University, Xi'an, 710038, China.ORCID https://orcid.org/0000-0003-4745-0298
Haiyang JiangDepartment of Neurosurgery, Tangdu Hospital, Air Force Military Medical University, Xi'an, 710038, China.ORCID https://orcid.org/0000-0002-6299-5213
Peng SunDepartment of Neurosurgery, Tangdu Hospital, Air Force Military Medical University, Xi'an, 710038, China.ORCID https://orcid.org/0000-0002-4311-1611
Yufeng LiuDepartment of Neurosurgery, Tangdu Hospital, Air Force Military Medical University, Xi'an, 710038, China.ORCID https://orcid.org/0000-0003-2921-6668
Xin JinDepartment of Nursing, Tangdu Hospital, Air Force Military Medical University, Xi'an, 710038, China.ORCID https://orcid.org/0000-0001-7772-3870

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIschemic stroke combined with hypertension can increase risks of stroke recurrence and death.

aimThe aim of this study is to investigate the clinical efficacy of clopidogrel bisulfate tablets combined with olmesartan medoxomil in the treatment of ischemic stroke patients with hypertension and the effect of angiotensin II type 1 receptor (AT

methodsNinety ischemic stroke patients with hypertension were chosen for continuous treatment with clopidogrel bisulfate tablets and olmesartan medoxomil for 12 months. The Modified Edinburgh Scandinavian Stroke Scale (MESSS) score, Brunnstrom score, Barthel score, death, recurrence, and progression of cerebrovascular residual lesions were observed and recorded during the treatment period. According to the plasma AT

resultsCompared with pretreatment, the MESSS scores of the patients at the first, second, third, sixth, ninth, and twelfth months after treatment were reduced (

conclusionClopidogrel bisulfate tablets combined with olmesartan medoxomil has prominent clinical effects in the treatment of ischemic stroke patients with hypertension, evidently improving the prognosis. In addition, the level of AT

Indexed as

AgedAngiotensin II Type 1 Receptor BlockersAntihypertensive AgentsClopidogrelComputational BiologyDrug Therapy, CombinationFemaleHumansHypertensionIschemic StrokeMaleMiddle AgedOlmesartan MedoxomilPlatelet Aggregation InhibitorsPrognosisReceptor, Angiotensin, Type 1Angiotensin II Type 1 Receptor BlockersAntihypertensive AgentsClopidogrelOlmesartan MedoxomilPlatelet Aggregation InhibitorsReceptor, Angiotensin, Type 1

Identifiers

PMID34745325
PMCPMC8566065
OpenAlexW3208699782

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.