Evidence map›Paper›PMID 34745278›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Effect of Tongluozhitong Prescription-Assisted Intra-Articular Injection of Sodium Hyaluronate on VAS Score and Knee Lysholm Score in Patients with Knee Osteoarthritis.

Jianfang Gong, Qiang Li, Mengling Wei, Liangliang Xue, Yinlian Liu, Jun Gao, Tiantian Qin

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jianfang GongDepartment of Traditional Chinese Medicine, Bethune Hospital, Taiyuan, Shanxi 030032, China.ORCID https://orcid.org/0000-0002-0912-2907
Qiang LiDepartment of Orthopaedics, Bethune Hospital, Taiyuan, Shanxi 030032, China.
Mengling WeiDepartment of Traditional Chinese Medicine, Bethune Hospital, Taiyuan, Shanxi 030032, China.
Liangliang XueDepartment of Radiology, Bethune Hospital, Taiyuan, Shanxi 030032, China.
Yinlian LiuDepartment of Rehabilitation, Bethune Hospital, Taiyuan, Shanxi 030032, China.
Jun GaoDepartment of Traditional Chinese Medicine, Bethune Hospital, Taiyuan, Shanxi 030032, China.
Tiantian QinDepartment of Traditional Chinese Medicine, Bethune Hospital, Taiyuan, Shanxi 030032, China.
Shanxi Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knee osteoarthritis (KOA) has become one of the leading causes of workforce loss in the middle-aged and elderly population and a global public health problem second only to cardiovascular disease, so we need to find more effective treatments for this disease. In this study, we selected 120 patients with KOA admitted to our hospital from June 2018 to December 2020 and divided them into treatment group 1, treatment group 2, and joint group according to the random number table method, with 40 patients in each group. Treatment group 1 was treated with Tongluozhitong prescription dip-soaking therapy, treatment 2 group was treated with intra-articular injection of sodium hyaluronate, and the joint group was treated with a combination of both modalities for 4 weeks in all three groups. Clinical efficacy, visual analogue scale (VAS), Lysholm knee score (LKS), activity of daily living score (ADL), the levels of bone metabolic markers such as cartilage oligomeric matrix protein (COMP), type II collagen degradation maker (CTX-II), and matrix metalloproteinase-3 (MMP-3), and the levels of inflammatory mediators such as interleukin-1

Identifiers

PMID34745278
PMCPMC8568548
OpenAlexW3209877089

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.