Evidence map›Paper›PMID 34745269›Full record

ReviewStem cells international2021

The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m

Weiwei Sun, Bin Zhang, Qingli Bie, Na Ma, Na Liu, Zewei Shao

Open access · goldAbstract readReview
In one paragraph

Review in Stem cells international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. The relevance of mJournal of cancer research and clinical oncology · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Pseudorabies virus exploits NFrontiers in microbiology · 2023
    Article
  6. Resetting the epigenome: Methylation dynamics in cancer stem cells.Frontiers in cell and developmental biology · 2022
    Review
  7. Article
  8. Frontiers in medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Weiwei SunInstitute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining, Shandong, China.ORCID https://orcid.org/0000-0003-3715-6650
Bin ZhangDepartment of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Qingli BieDepartment of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Na MaInstitute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining, Shandong, China.
Na LiuInstitute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining, Shandong, China.
Zewei ShaoInstitute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining, Shandong, China.ORCID https://orcid.org/0000-0002-6125-275X
Jining Medical University · CNAffiliated Hospital of Jining Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biological role of RNA methylation in stem cells has attracted increasing attention. Recent studies have demonstrated that RNA methylation plays a crucial role in self-renewal, differentiation, and tumorigenicity of stem cells. In this review, we focus on the biological role of RNA methylation modifications including N6-methyladenosine, 5-methylcytosine, and uridylation in embryonic stem cells, adult stem cells, induced pluripotent stem cells, and cancer stem cells, so as to provide new insights into the potential innovative treatments of cancer or other complex diseases.

Identifiers

PMID34745269
PMCPMC8568546
OpenAlexW3208892426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.