ReviewInternational journal of dentistry2021
Taxonomic Analysis of Oral Microbiome during Orthodontic Treatment.
Review in International journal of dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Material Properties of Composite Resins Used for Orthodontic Attachments in Clear Aligner Therapy: A Systematic Review.Biomolecules · 2026Pooled it
- Impact of Clear Aligners on the Oral Microbiome: A Systematic Review of Current Evidence.Clinical and experimental dental research · 2026Pooled it
- Oral Microbiome and Metabolome Changes During Orthodontic Treatments: A Systematic Review of Limited Clinical Evidence.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Influence of elastomeric and steel ligatures on periodontal health during fixed appliance orthodontic treatment: a systematic review and meta-analysis.Progress in orthodontics · 2024Pooled it
- Oral mucosal wound healing: A photograph-based prospective study.Journal of periodontology · 2026Article
- Orthodontic Extrusion in Daily Clinical Practice: Management of Fractured or Damaged Anterior Teeth.Journal of personalized medicine · 2025Review
- Evaluation of the Possible Correlation Between Dental Occlusion and Craniomandibular Disorders by Means of TeethanJournal of clinical medicine · 2025Article
- Effects of removable clear dental aligners on the composition of the oral microbiome.Journal of oral microbiology · 2025Article
- Acquisition of the Oral Microbiome.Advances in experimental medicine and biology · 2025Review
- Comparative characterization of supragingival plaque microbiomes in malocclusion adult female patients undergoing orthodontic treatment with removable aligners or fixed appliances: a descriptive cross-sectional study.Frontiers in cellular and infection microbiology · 2024Article
- Supragingival microbiome variations and the influence ofJournal of oral microbiology · 2024Article
- Profile of Orthodontic Use across Demographics.Dentistry journal · 2023Article
- Impact of Clear Aligners on Oral Health and Oral Microbiome During Orthodontic Treatment.International dental journal · 2023Review
- Article
- The three-dimensional displacement tendency of teeth depending on incisor torque compensation with clear aligners of different thicknesses in cases of extraction: a finite element study.BMC oral health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrthodontic appliances induce significant changes in the oral microbiome, but this shift in microbial composition has not been well established by the available evidence yet.
objectivesTo perform a systematic review of existing literature in order to assess the taxonomic microbial changes in orthodontic patients during Fixed Appliance Treatment (FAT) and Clear Aligner Treatment (CAT), using next-generation sequencing (NGS) technique of the bacterial 16S rRNA gene.
resultsThe initial search identified 393 articles, 74 of which were selected by title and abstract. After full-text reading, six articles were selected according to inclusion criteria. The evidence quality for all the studies was moderate.
conclusionsOrthodontic treatment seems to transiently affect the composition of subgingival microbiome, although not salivary, maintaining a stable microbial diversity. Different results were found in the shift of microbiome between plaque and saliva, depending on the type of orthodontic treatment. This review should be interpreted with some caution because of the number, quality, and heterogeneity of the included studies.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.