Evidence map›Paper›PMID 34745151›Full record

ArticleFrontiers in immunology2021

CRAC Channel Controls the Differentiation of Pathogenic B Cells in Lupus Nephritis.

Xue Li, Qin Zeng, Shuyi Wang, Mengyuan Li, Xionghui Chen, Yuefang Huang, Binfeng Chen, Mianjing Zhou, Yimei Lai, Chaohuan Guo and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. CRAC channels as targets for immunotherapy.Current opinion in immunology · 2026
    Review
  2. Article
  3. Orai1 acts as a novel CaExperimental & molecular medicine · 2026
    Article
  4. Article
  5. Article
  6. Aberrant METTL1-mediated tRNA mNature communications · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Xue LiDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Qin ZengDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Shuyi WangDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Mengyuan LiDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xionghui ChenDepartment of Nephrology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yuefang HuangDepartment of Pediatrics, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Binfeng ChenDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Mianjing ZhouDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yimei LaiDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Chaohuan GuoDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Siyuan ZhaoDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Hui ZhangDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Niansheng YangDepartment of Rheumatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Store-operated Ca

Indexed as

AnimalsB-LymphocytesCalcium Release Activated Calcium ChannelsCell DifferentiationHumansLupus NephritisMiceMice, Inbred MRL lprCalcium Release Activated Calcium ChannelsB-cell differentiationCa2+ release-activated Ca2+ channelCaMK2lupus nephritisstore-operated Ca2+ entry

Identifiers

PMID34745151
PMCPMC8569388
OpenAlexW3209452364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.