Evidence map›Paper›PMID 34745141›Full record

ArticleFrontiers in immunology2021

Polysaccharides From the Roots of

Xiaogang Chen, Wenjing Sun, Baichang Xu, Enyun Wu, Yao Cui, Kaiyuan Hao, Geyin Zhang, Congcong Zhou, Yanping Xu, Jiang Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 68 citations in OpenAlex.

  1. Animals : an open access journal from MDPI · 2026
    Article
  2. Foods (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Journal of microbiology and biotechnology · 2026
    Article
  5. Effects ofFrontiers in microbiology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Foods (Basel, Switzerland) · 2025
    Review
  14. Article
  15. Deciphering the immunomodulatory mechanisms ofFrontiers in cell and developmental biology · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Extracellular vesicles enhance theFrontiers in chemistry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Xiaogang ChenCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Wenjing SunCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Baichang XuCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Enyun WuCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Yao CuiCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Kaiyuan HaoCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Geyin ZhangCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Congcong ZhouCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Yanping XuCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Jiang LiCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Hongbin SiCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Guangxi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclophosphamide (CTX), a common anticancer drug, can cause a variety of side effects such as immunosuppression and intestinal mucosal injury. Polysaccharides are the major bioactive components of the roots of

Indexed as

MillettiaPrebioticsAdjuvants, ImmunologicAnimalsCyclophosphamideCytokinesDysbiosisFatty Acids, VolatileFecesFemaleGastrointestinal MicrobiomeImmunoglobulin GImmunosuppression TherapyImmunosuppressive AgentsIntestinesMaleAdjuvants, ImmunologicCyclophosphamideCytokinesFatty Acids, VolatileImmunoglobulin GImmunosuppressive AgentsPolysaccharidesPrebioticscyclophosphamidegut microbiotaimmunoregulationintestinal barrier injuryMillettia Speciosa Champpolysaccharides

Identifiers

PMID34745141
PMCPMC8567740
OpenAlexW3210031471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.