Evidence map›Paper›PMID 34745138›Full record

ArticleFrontiers in immunology2021

Semi-Automated Live Tracking of Microglial Activation in CX3CR1

Moritz J Frenger, Christina Hecker, Mustafa Sindi, Andrea Issberner, Hans-Peter Hartung, Sven G Meuth, Michael Dietrich, Philipp Albrecht

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Moritz J FrengerDepartment of Neurology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Christina HeckerDepartment of Neurology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Mustafa SindiDepartment of Neurology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Andrea IssbernerDepartment of Neurology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Hans-Peter HartungDepartment of Neurology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Sven G MeuthDepartment of Neurology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Michael DietrichDepartment of Neurology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Philipp AlbrechtDepartment of Neurology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
Heinrich Heine University Düsseldorf · DEUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Confocal scanning laser ophthalmoscopy (cSLO) is a non-invasive technique for real-time imaging of the retina. We developed a step-by-step protocol for the semi-automatic evaluation of myeloid cells in cSLO images from CX3CR1

Indexed as

AnimalsCX3C Chemokine Receptor 1Encephalomyelitis, Autoimmune, ExperimentalFemaleGreen Fluorescent ProteinsMaleMice, TransgenicMicrogliaOphthalmoscopyRetinaTomography, Optical CoherenceCX3C Chemokine Receptor 1Cx3cr1 protein, mouseGreen Fluorescent Proteinsconfocal scanning laser ophthalmoscopyCX3CR1-GFPexperimental autoimmune encephalomyelitislive-trackingmicroglia

Identifiers

PMID34745138
PMCPMC8567040
OpenAlexW3208630705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.