Evidence map›Paper›PMID 34745086›Full record

ArticleFrontiers in immunology2021

Oxalate Alters Cellular Bioenergetics, Redox Homeostasis, Antibacterial Response, and Immune Response in Macrophages.

Parveen Kumar, Kanchan Saini, Vikram Saini, Tanecia Mitchell

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  8. Observational
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  12. Oxalate homeostasis.Nature reviews. Nephrology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Parveen KumarDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL, United States.
Kanchan SainiLaboratory of Infection Biology and Translational Research, Department of Biotechnology, All India Institute of Medical Sciences, New Delhi, India.
Vikram SainiLaboratory of Infection Biology and Translational Research, Department of Biotechnology, All India Institute of Medical Sciences, New Delhi, India.
Tanecia MitchellDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL, United States.
Department of Biotechnology · INUniversity of Alabama at Birmingham · US

Funding

UAB-UCSD O'Brien Core Center for Acute Kidney Injury ResearchP30DK079337 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AGARWAL, ANUPAM · 2008 to 2022
$18.3M
Monocyte Mitochondrial Dysfunction and Kidney Stone DiseaseK01DK106284 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MITCHELL, TANECIA R · 2016 to 2021
$912k
Dietary Oxalate and Innate Immunity in Kidney Stone DiseaseR03DK123542 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MITCHELL, TANECIA R · 2020 to 2021
$216k
NIDDK NIH HHS K01 DK106284NIDDK NIH HHS P30 DK079337NIDDK NIH HHS R03 DK123542
6 · The paper itself

Abstract

Individuals with calcium oxalate (CaOx) kidney stones can have secondarily infected calculi which may play a role in the development of recurrent urinary tract infection (UTI). Uropathogenic

Indexed as

Adenosine TriphosphateAnimalsBacterial InfectionsCytokinesEnergy MetabolismHomeostasisHumansMacrophagesMaleMiceMice, Inbred C57BLOxalatesOxidation-ReductionTHP-1 CellsAdenosine TriphosphateCytokinesOxalatescellular bioenergeticsEscherichia coliinflammationkidney stonemacrophageoxalateredox homeostasis

Identifiers

PMID34745086
PMCPMC8566947
OpenAlexW3208961373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.