Evidence map›Paper›PMID 34745038›Full record

ArticleFrontiers in microbiology2021

Flavonoid Library Screening Reveals Kaempferol as a Potential Antiviral Agent Against African Swine Fever Virus.

Erik Arabyan, Astghik Hakobyan, Tamara Hakobyan, Rafaella Grigoryan, Roza Izmailyan, Aida Avetisyan, Zaven Karalyan, Joshua A Jackman, Fernando Ferreira, Charles C Elrod and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Identification ofMicrobiology spectrum · 2025
    Article
  12. Review
  13. Flavonoid compound fromFrontiers in cellular and infection microbiology · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Erik ArabyanLaboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, Yerevan, Armenia.
Astghik HakobyanLaboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, Yerevan, Armenia.
Tamara HakobyanLaboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, Yerevan, Armenia.
Rafaella GrigoryanLaboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, Yerevan, Armenia.
Roza IzmailyanLaboratory of Cell Biology and Virology, Institute of Molecular Biology of NAS, Yerevan, Armenia.
Aida AvetisyanLaboratory of Cell Biology and Virology, Institute of Molecular Biology of NAS, Yerevan, Armenia.
Zaven KaralyanLaboratory of Cell Biology and Virology, Institute of Molecular Biology of NAS, Yerevan, Armenia.
Joshua A JackmanSchool of Chemical Engineering, Sungkyunkwan University, Suwon, South Korea.
Fernando FerreiraFaculdade de Medicina Veterinária, Centro de Investigação Interdisciplinar em Sanidade Animal, Universidade de Lisboa, Avenida da Universidade Técnica, Lisboa, Portugal.
Charles C ElrodNatural Biologics Inc., Newfield, NY, United States.
Hovakim ZakaryanLaboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, Yerevan, Armenia.
Institute of Molecular Biology · AMCornell University · USSungkyunkwan University · KRUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naturally occurring plant flavonoids are a promising class of antiviral agents to inhibit African swine fever virus (ASFV), which causes highly fatal disease in pigs and is a major threat to the swine industry. Currently known flavonoids with anti-ASFV activity demonstrate a wide range of antiviral mechanisms, which motivates exploration of new antiviral candidates within this class. The objective of this study was to determine whether other flavonoids may significantly inhibit ASFV infection

Indexed as

antiviralautophagyflavonoidkaempferolscreening

Identifiers

PMID34745038
PMCPMC8567988
OpenAlexW3206675796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.