Evidence map›Paper›PMID 34744983›Full record

SynthesisFrontiers in neurology2021

Serum Aquaporin 4-Immunoglobulin G Titer and Neuromyelitis Optica Spectrum Disorder Activity and Severity: A Systematic Review and Meta-Analysis.

Jia Liu, Guojun Tan, Bin Li, Jingze Zhang, Ying Gao, Yuanbo Cao, Zhen Jia, Kazuo Sugimoto

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Neuroglial markers of damage in autoimmune neurology.Therapeutic advances in neurological disorders · 2026
    Review
  4. Article
  5. Article
  6. Review
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Jia LiuDepartment of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Guojun TanDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Bin LiDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Jingze ZhangDepartment of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Ying GaoDepartment of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yuanbo CaoDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Zhen JiaDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Kazuo SugimotoDepartment of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Hebei Medical University · CNBeijing University of Chinese Medicine · CNChinese Institute for Brain Research · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNSecond Hospital of Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

aquaporin4-immunoglobulin Gbiomarkerclinical relevancemeta-analysisneuromyelitis optica spectrum disorder

Identifiers

PMID34744983
PMCPMC8565925
OpenAlexW3206939395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.