Evidence map›Paper›PMID 34744974›Full record

ArticleFrontiers in neurology2021

The Relationship of

Danielle S Powell, Pei-Lun Kuo, Riaz Qureshi, Sally B Coburn, David S Knopman, Priya Palta, Rebecca Gottesman, Michael Griswold, Marilyn Albert, Jennifer A Deal and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. The Association BetweenNeurology. Genetics · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. APOE ε4 is associated with earlier symptom onset in LOAD but later symptom onset in EOAD.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Danielle S PowellDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, United States.
Pei-Lun KuoDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, United States.
Riaz QureshiDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, United States.
Sally B CoburnDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, United States.
David S KnopmanDepartment of Neurology, Mayo Clinic, Rochester, MN, United States.
Priya PaltaDivision of General Medicine, Columbia University Medical Center, New York, NY, United States.
Rebecca GottesmanDepartment of Neurology, Johns Hopkins University, Baltimore, MD, United States.
Michael GriswoldBiostatistics, School of Medicine, University of Mississippi Medical Center, Jackson, MS, United States.
Marilyn AlbertDepartment of Neurology, Johns Hopkins University, Baltimore, MD, United States.
Jennifer A DealDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, United States.
Alden L GrossDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, United States.
Johns Hopkins University · USColumbia University Irving Medical Center · USMayo Clinic in Arizona · USUniversity of Mississippi Medical Center · US

Funding

ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028U01HL096812 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, THOMAS H MOSLEY · 2010 to 2026
$65.7M
NHLBI NIH HHS U01 HL096812
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

apolipoprotein ε allelecognitive agingdementiaepidemiologygeneticsracesex

Identifiers

PMID34744974
PMCPMC8564142
OpenAlexW3206421888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.