ReviewFrontiers in psychiatry2021
Prediction and Prevention in the Clinical High-Risk for Psychosis Paradigm: A Review of the Current Status and Recommendations for Future Directions of Inquiry.
Review in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- On the proportion of patients who experience a prodrome prior to psychosis onset: A systematic review and meta-analysis.Molecular psychiatry · 2024Pooled it
- Predictors of transition in patients with clinical high risk for psychosis: an umbrella review.Translational psychiatry · 2023Pooled it
- Race/ethnicity and socioeconomic status as predictors of outcome following family therapy in youth at clinical high risk for psychosis.Early intervention in psychiatry · 2024Trial
- Incidence, Prevalence, and Stability of Remission in Individuals With Clinical High Risk for Psychosis.JAMA network open · 2025Article
- Presence of Psychotic Spectrum Symptoms Before Age 12 in Schizophrenia Patients: A Retrospective Study on Clinical Implications for Early Detection and Intervention.Brain sciences · 2025Article
- Three-year course of clinical high-risk symptoms for psychosis in the community: a latent class analysis.Epidemiology and psychiatric sciences · 2025Article
- Self-Transcendence as a Risk and Resilience Factor in Individuals at Clinical High Risk for Psychosis.Early intervention in psychiatry · 2025Article
- A narrative literature review of white matter microstructure in individuals at clinical high risk for psychosis.Psychoradiology · 2025Review
- Sensitivity of the familial high-risk approach for the prediction of future psychosis: a total population study.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- Recent onset mental illness severity: pilot study on the role of cognition, sensory modulation, and daily life participation.Frontiers in psychiatry · 2024Article
- Risk for psychiatric and substance use disorders as a function of transitions in Sweden's public educational system: a national study.Psychological medicine · 2024Article
- Correlations between Negative Symptoms and Cognitive Deficits in Individuals at First Psychotic Episode or at High Risk of Psychosis: A Systematic Review.Journal of clinical medicine · 2023Review
- Accelerating Medicines PartnershipWorld psychiatry : official journal of the World Psychiatric Association (WPA) · 2023Article
- The role of mentalizing in the relationship between schizotypal personality traits and state signs of psychosis risk captured by cognitive and perceptive basic symptoms.Frontiers in psychiatry · 2023Article
- Management of Psychosis and Schizophrenia by Primary Care GPs: A Cross-Sectional Study in Spain.Journal of primary care & community healthArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prediction and prevention of negative clinical and functional outcomes represent the two primary objectives of research conducted within the clinical high-risk for psychosis (CHR-P) paradigm. Several multivariable "risk calculator" models have been developed to predict the likelihood of developing psychosis, although these models have not been translated to clinical use. Overall, less progress has been made in developing effective interventions. In this paper, we review the existing literature on both prediction and prevention in the CHR-P paradigm and, primarily, outline ways in which expanding and combining these paths of inquiry could lead to a greater improvement in individual outcomes for those most at risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.