SynthesisFrontiers in psychiatry2021
Traumatic Events, Social Adversity and Discrimination as Risk Factors for Psychosis - An Umbrella Review.
Synthesis in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 42 citations in OpenAlex.
- Childhood Adversities and Psychosis Across Populations: Insights From the 6-Country EU-GEI Study.Schizophrenia bulletin · 2026Article
- Social Defeat and Psychosis in the United States: A Replication and Critical Reconceptualization.Schizophrenia bulletin · 2026Article
- Prevalence and associated risk factors of psychotic experiences in the general population during the COVID-19 pandemic: a systematic review and meta-analysis.Annals of general psychiatry · 2026Article
- Contrast sensitivity and subjective visual disturbances across the psychosis continuum.Cognitive neuropsychiatry · 2026Article
- A collective narrative of care and complex mental illness.Health (London, England : 1997) · 2025Article
- Policy paper of the Committee on Ethics and Task Force on Migration and Mental Health: Migration and mental health of migrants, refugees, asylum seekers - Ethical dilemmas and concerns.European psychiatry : the journal of the Association of European Psychiatrists · 2025Review
- Neighborhood social fragmentation in relation to impaired mismatch negativity among youth at clinical high risk for psychosis and healthy comparisons.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Reimagining psychosis prevention: responding to the accessibility issues of At-Risk Mental State (ARMS) services through a selective public health approach.BJPsych bulletin · 2025Article
- Annual Research Review: Psychosis in children and adolescents - a call to action: a commentary on Kelleher (2025).Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- The role of trauma, attachment, and voice-hearer's appraisals: a latent profile analysis in the AVATAR2 trial.Psychological medicine · 2025Article
- Neuroimaging stratification reveals the striatal vulnerability to stress as a risk for schizophrenia.Translational psychiatry · 2025Article
- The association between neighborhood-level social fragmentation and distressing psychotic-like experiences in early adolescence: the moderating role of close friends.Psychological medicine · 2024Article
- Ruminative thinking mediates the effects of exposure to adverse life events on psychotic-like experiences.Frontiers in psychology · 2024Article
- Level of structural integration in people with schizophrenia and schizoaffective disorders - applicability and associations with clinical parameters.Frontiers in psychiatry · 2024Article
- Factors associated with the psychosis continuum among homeless people: Comparison between natives and migrants in the SAMENTA study.Journal of migration and health · 2024Article
- Review of Major Social Determinants of Health in Schizophrenia-Spectrum Psychotic Disorders: I. Clinical Outcomes.Schizophrenia bulletin · 2023Review
- Review of Major Social Determinants of Health in Schizophrenia-Spectrum Psychotic Disorders: III. Biology.Schizophrenia bulletin · 2023Article
- Social adversity during juvenile age but not adulthood increases susceptibility to an immune challenge later in life.Neurobiology of stress · 2023Article
- Linguistic findings in persons with schizophrenia-a review of the current literature.Frontiers in psychology · 2023Review
- The weaponization of medicine: Early psychosis in the Black community and the need for racially informed mental healthcare.Frontiers in psychiatry · 2023Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure to childhood trauma is a well-known risk factor for severe mental disorders including schizophrenia and other non-affective psychoses. Beyond childhood trauma, there is increasing evidence that bullying, social exclusion, and discrimination during adolescence and adulthood may increase the risk of developing a psychotic disorder, and that such forms of traumatization may also underlie the elevated psychosis risk among migrants or persons with a visible minority status. In this umbrella review, we systematically assess meta-analyses regarding trauma and social adversity. A systematic literature review yielded 11 meta-analyses that met inclusion criteria and could be summarized quantitatively with a random effect model. Furthermore, six meta-analyses were evaluated qualitatively. Heterogeneity and publication bias were apparent in several meta-analyses. We observed that most significant social risk factors for psychosis were vulnerability for racist discrimination [OR = 3.90 (3.25-4.70)], migration [OR = 2.22 (1.75-2.80)], and childhood adversities [OR = 2.81 (2.03-3.83)]. Furthermore, social factors increasing the risk for psychosis were variation/impairment of parental communication, aversive adult life events, bullying, and factors associated with social isolation and discrimination. In spite of these environmental risk factors, there is a lack of evidence regarding treatment of trauma and psychosis, although some psychotherapeutic and art therapy approaches appear to be promising. Beyond individual interventions, stigmatization, racism, and other forms of discrimination need to be targeted to increase solidarity and communal support.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.