Evidence map›Paper›PMID 34744799›Full record

ReviewFrontiers in physiology2021

BK Channel Gating Mechanisms: Progresses Toward a Better Understanding of Variants Linked Neurological Diseases.

Jianmin Cui

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Application of Modulators of CaInternational journal of molecular sciences · 2025
    Article
  4. Cytochrome C-like Domain Within the Human BK Channel.International journal of molecular sciences · 2025
    Article
  5. Article
  6. Large conductance voltage-and calcium-activated KFrontiers in pharmacology · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Cholesterol and PIPAdvances in experimental medicine and biology · 2023
    Article
  12. KCurrent neuropharmacology · 2023
    Review
  13. Article
  14. Evidence for Dual Activation ofInternational journal of molecular sciences · 2022
    Article
  15. Neuronal mechanism of a BK channelopathy in absence epilepsy and dyskinesia.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jianmin CuiDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Disorders, Cardiac Bioelectricity and Arrhythmia Center, Washington University, St. Louis, MO, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The large conductance Ca

Indexed as

activationBK channelcalciumgain of function mutationloss of function mutationneurological disordersvoltage

Identifiers

PMID34744799
PMCPMC8567085
OpenAlexW3208240657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.