Evidence map›Paper›PMID 34744753›Full record

ArticleFrontiers in pharmacology2021

Repurposing Cefazolin-Avibactam for the Treatment of Drug Resistant

Shashikant Srivastava, Tawanda Gumbo, Tania Thomas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. DynamicAntibiotics (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shashikant SrivastavaDepartment of Pulmonary Immunology, University of Texas Health Science Centre, Tyler, TX, United States.
Tawanda GumboPraedicare Laboratories and Quantitative Preclinical & Clinical Sciences Department, Praedicare Inc., Dallas, TX, United States.
Tania ThomasDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, United States.
Southwestern Medical CenterUniversity of Virginia · US

Funding

PK-PD of combination antituberculosis therapy for suppression of drug-resistanceR01AI079497 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI GUMBO, TAWANDA · 2008 to 2011
$2.3M
PK/PD Optimized Cephalosporins Based Treatment Regimens for Children With MDR-TBR01HD099756 · NICHD · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI KANT, SHASHI · 2019 to 2023
$1.6M
Short course therapy for MDR-TB based on PK/PD answers for biological variabilityR56AI111985 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI GUMBO, TAWANDA · 2014 to 2014
$900k
NIAID NIH HHS R01 AI079497NIAID NIH HHS R56 AI111985NICHD NIH HHS R01 HD099756
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

avibactambeta-lactamcephalosporinmultidrug resistant tuberculosisoptimal dose

Identifiers

PMID34744753
PMCPMC8569112
OpenAlexW3214091792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.