Evidence map›Paper›PMID 34744682›Full record

ArticleFrontiers in aging neuroscience2021

Disrupted Brain Connectivity Networks in Aphasia Revealed by Resting-State fMRI.

Xiaoyun Chen, Liting Chen, Senning Zheng, Hong Wang, Yanhong Dai, Zhuoming Chen, Ruiwang Huang

Open access · greenAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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  16. Aberrant beta-band brain connectivity predicts speech motor planning deficits in post-stroke aphasia.Cortex; a journal devoted to the study of the nervous system and behavior · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiaoyun ChenDepartment of Rehabilitation, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Liting ChenMedical Imaging Center, First Affiliated Hospital of Jinan University, Guangzhou, China.
Senning ZhengKey Laboratory of Mental Health and Cognitive Science of Guangdong, Center for the Study of Applied Psychology and MRI Center, School of Psychology, Institute of Brain Research and Rehabilitation (IBRR), South China Normal University, Guangzhou, China.
Hong WangDepartment of Rehabilitation, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Yanhong DaiDepartment of Rehabilitation, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Zhuoming ChenDepartment of Rehabilitation, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Ruiwang HuangKey Laboratory of Mental Health and Cognitive Science of Guangdong, Center for the Study of Applied Psychology and MRI Center, School of Psychology, Institute of Brain Research and Rehabilitation (IBRR), South China Normal University, Guangzhou, China.
First Affiliated Hospital of Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aphasia is characterized by the disability of spontaneous conversation, listening, understanding, retelling, naming, reading, or writing. However, the neural mechanisms of language damage after stroke are still under discussion. This study aimed to investigate the global and nodal characterization of the functional networks in patients with aphasic stroke based on resting-state functional MRI (fMRI). Twenty-four right-handed patients with aphasia after stroke and 19 healthy controls (HC) underwent a 3-TfMRI scan. A whole-brain large-scale functional connectivity network was then constructed based on Power's atlas of 264 functional regions of interest, and the global and nodal topological properties of these networks were analyzed using graph theory approaches. The results showed that patients with aphasia had decreased in small-worldness (sigma), normalized clustering coefficient (gamma), and local efficiency (

Indexed as

aphasiacognitive impairmentfunctional MRIstroketopological properties

Identifiers

PMID34744682
PMCPMC8565294
OpenAlexW3210912389

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.