Evidence map›Paper›PMID 34744477›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2021

Total ginsenosides promote the IEC-6 cell proliferation via affecting the regulatory mechanism mediated by polyamines.

Yiping Zhu, Anrong Wang, Ruliu Li, Huibin Zhu, Ling Hu, Weiwen Chen

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Citric Acid Promotes Immune Function by Modulating the Intestinal Barrier.International journal of molecular sciences · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yiping ZhuPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, 12 Jichang road, Guangzhou 510405, PR China.
Anrong WangPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, 12 Jichang road, Guangzhou 510405, PR China.
Ruliu LiPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, 12 Jichang road, Guangzhou 510405, PR China.
Huibin ZhuPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, 12 Jichang road, Guangzhou 510405, PR China.
Ling HuPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, 12 Jichang road, Guangzhou 510405, PR China.
Weiwen ChenPi-wei Institute, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, 12 Jichang road, Guangzhou 510405, PR China.
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial cell proliferation has been demonstrated to be a critical modality for mucosal repair after gastrointestinal mucosal injury. This research aimed to investigate the effect of total ginsenosides upon the proliferation of intestinal epithelial cells (IEC-6), and elucidate its potential mechanisms through polyamine-regulated pathway including the expression of proliferation-related proteins. Total ginsenosides (PGE3) were extracted from

Indexed as

Cdk2, cyclin-dependent protein kinase 2Cell cycleCell proliferationDFMO, DL-α-difluoromethylornithineIEC-6, intestinal epithelial cellsIntestinal epithelial cellsPGE1, Panax ginseng aqueous extractsPGE3, total ginsenosidesPGE, Panax ginseng extractsProtein expressionRhoA, Ras homolog family member ARQSS, reinforcing Qi strengthening spleenTotal ginsenosides

Identifiers

PMID34744477
PMCPMC8551508
OpenAlexW3199397135

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.