Evidence map›Paper›PMID 34744194›Full record

ArticleTetrahedron2021

High-throughput screening of α-chiral-primary amines to determine yield and enantiomeric excess.

Sarah R Moor, James R Howard, Brenden T Herrera, Eric V Anslyn

Abstract read
In one paragraph

Article in Tetrahedron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Determination of Enantiomeric Excess by Optofluidic Microlaser near Exceptional Point.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah R MoorDepartment of Chemistry, The University of Texas at Austin, Austin, TX 78712, USA.ORCID 0000-0001-5579-407X
James R HowardDepartment of Chemistry, The University of Texas at Austin, Austin, TX 78712, USA.ORCID 0000-0002-9184-6954
Brenden T HerreraDepartment of Chemistry, The University of Texas at Austin, Austin, TX 78712, USA.ORCID 0000-0001-6151-947X
Eric V AnslynDepartment of Chemistry, The University of Texas at Austin, Austin, TX 78712, USA.ORCID 0000-0002-5137-8797

Funding

Bruker AVANCE III HD 500 MHz NMRS10OD021508 · OD · UNIVERSITY OF TEXAS AT AUSTIN · PI SESSLER, JONATHAN L · 2016 to 2016
$529k
NIH HHS S10 OD021508
6 · The paper itself

Abstract

A novel screening protocol was developed using a combination of a fluorescent indicator displacement assay and a circular dichroism (CD) active Fe(II) complex to determine concentration and enantiomeric excess (

Indexed as

Circular DichroismFluorescenceHigh-throughput screeningIndicator displacement assay

Identifiers

PMID34744194
PMCPMC8568316

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.