Evidence map›Paper›PMID 34744107›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19.

Norihito Omote, Yoshihiro Kanemitsu, Takahiro Inoue, Toshiyuki Yonezawa, Takuji Ichihashi, Yuichiro Shindo, Koji Sakamoto, Akira Ando, Atsushi Suzuki, Akio Niimi and 3 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Acute exacerbation in fibrotic interstitial lung disease: an international working group report.American journal of respiratory and critical care medicine · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Norihito OmoteDepartment of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan.
Yoshihiro KanemitsuDepartment of Internal Medicine, Aichi Prefectural Hospital, Japan.
Takahiro InoueDepartment of Internal Medicine, Aichi Prefectural Hospital, Japan.
Toshiyuki YonezawaDepartment of Internal Medicine, Aichi Prefectural Hospital, Japan.
Takuji IchihashiDepartment of Internal Medicine, Aichi Prefectural Hospital, Japan.
Yuichiro ShindoDepartment of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan.
Koji SakamotoDepartment of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan.
Akira AndoDepartment of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan.
Atsushi SuzukiDepartment of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan.
Akio NiimiDepartment of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Japan.
Satoru ItoDepartment of Respiratory Medicine and Allergology, Aichi Medical University, Japan.
Kazuyoshi ImaizumiDepartment of Respiratory Medicine, Fujita Health University School of Medicine, Japan.
Naozumi HashimotoDepartment of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan.
Nagoya University · JPAichi Medical University · JPFujita Health University · JPNagoya City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a case of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) triggered by COVID-19. An 87-year-old woman tested positive for COVID-19 on a polymerase chain reaction test, and computed tomography revealed ground-glass opacity (GGO) superimposed on a background pattern consistent with usual interstitial pneumonia. Considering these data, we diagnosed her with AE-IPF. She experienced worsening of dyspnea and expansion of the GGO. Therefore, we introduced high-dose steroids (methylprednisolone 250 mg/day for 3 days). After the treatment, the pulmonary infiltrates improved. She was discharged from our hospital without severe disability. High-dose steroids can be a viable treatment option for AE-IPF triggered by COVID-19.

Indexed as

COVID-19Idiopathic Pulmonary FibrosisAged, 80 and overDisease ProgressionFemaleHumansSARS-CoV-2SteroidsSteroidsacute exacerbationcase reportCOVID-19high-dose steroididiopathic pulmonary fibrosis

Identifiers

PMID34744107
PMCPMC8851168
OpenAlexW3211353027

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.