Evidence map›Paper›PMID 34743990›Full record

ReviewMetabolism: clinical and experimental2022

Regulation of NAD

Xiaogang Chu, Raghavan Pillai Raju

Open access · greenAbstract readReview
In one paragraph

Review in Metabolism: clinical and experimental, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 94 citations in OpenAlex.

  1. Trial
  2. Gut microbes · 2026
    Article
  3. Article
  4. NMN Can Restore Ovarian Reserve in Aged Mice by Upregulating NADReproductive sciences (Thousand Oaks, Calif.) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. NRH, a potent NADMetabolism: clinical and experimental · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xiaogang ChuDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States of America.
Raghavan Pillai RajuDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States of America. Electronic address: rraju@augusta.edu.
Augusta University · US

Funding

Reparative effect of juvenile factors in aging and injuryR01AG073338 · NIA · AUGUSTA UNIVERSITY · PI Raghavan Pillai Raju · 2022 to 2026
$2.8M
Metabolic alterations in hemorrhagic shockR01GM122059 · NIGMS · AUGUSTA UNIVERSITY · PI RAJU, RAGHAVAN PILLAI · 2017 to 2020
$1.2M
Reparative effect of juvenile factors in aging and injuryR56AG073338 · NIA · AUGUSTA UNIVERSITY · PI RAJU, RAGHAVAN PILLAI · 2021 to 2021
$316k
NIA NIH HHS R01 AG073338NIA NIH HHS R56 AG073338NIGMS NIH HHS R01 GM122059
6 · The paper itself

Abstract

More than a century after discovering NAD

Indexed as

AgingAnimalsCardiovascular DiseasesDiabetes MellitusHumansMitochondriaNADSignal TransductionNADNADNiacinNiacin receptorNicotinamide adenine mononucleotideNicotinamide riboside

Identifiers

PMID34743990
PMCPMC8649045
OpenAlexW3210712229

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.