Evidence map›Paper›PMID 34743832›Full record

ReviewThe Journal of allergy and clinical immunology2021

Structural racism and its pathways to asthma and atopic dermatitis.

Adali Martinez, Rosemarie de la Rosa, Mahasin Mujahid, Neeta Thakur

Abstract readReview
In one paragraph

Review in The Journal of allergy and clinical immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Socioeconomic status and acculturation as determinants of atopic disease prevalence in United States Latino children.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Article
  5. Article
  6. Article
  7. Socioeconomic deprivation performs equally to race in the Pediatric Asthma Risk Score.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. State-level structural racism and sleep disturbances among Black and Latinx adolescents: Findings from the adolescent brain cognitive development study.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  13. Managing childhood asthma with an eye toward environmental, social, and behavioral features.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Influence of ADRB2 variants on bronchodilator response and asthma control in a mixed population.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adali MartinezSchool of Medicine, the University of California San Francisco, San Francisco, Calif.
Rosemarie de la RosaSchool of Public Health, University of California Berkeley, Berkeley, Calif.
Mahasin MujahidSchool of Public Health, University of California Berkeley, Berkeley, Calif.
Neeta ThakurSchool of Medicine, the University of California San Francisco, San Francisco, Calif. Electronic address: Neeta.Thakur@ucsf.edu.

Funding

Social adversities and asthma: a new phenotype?K23HL125551 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THAKUR, NEETA · 2016 to 2020
$1.0M
NHLBI NIH HHS K23 HL125551
6 · The paper itself

Abstract

Black, Latinx, and Indigenous people in the United States experience a disproportionate burden of asthma and atopic dermatitis. The study of these disease disparities has focused on proximal socioenvironmental exposures and on the biomechanistic (including genetic) differences between racial and ethnic groups. Although biomedical research in allergy and immunology stands to benefit from the inclusion of diverse study populations, the narrow focus on biologic mechanisms disregards the complexity of interactions across biologic and structural factors, including the effects of structural racism. Structural racism is the totality of ways in which society fosters discrimination by creating and reinforcing inequitable systems through intentional policies and practices sanctioned by government and institutions. It is embedded across multiple levels, including the economic, educational, health care, and judicial systems, which are manifested in inequity in the physical and social environment. In this review, we present a conceptual framework and pull from the literature to demonstrate how structural racism is a root cause of atopic disease disparities by way of residential segregation, socioeconomic position, and mass incarceration, which may lead to aberrations in the innate and adaptive immune response and the augmentation of physiologic stress responses, contributing to a disproportionate disease burden for racial and ethnic populations.

Indexed as

EthnicityHealthcare DisparitiesHealth Status DisparitiesRacismAsthmaDermatitis, AtopicHumansUnited Statesallergic dermatitisasthmaatopyhealth disparitiesRacism

Identifiers

PMID34743832
PMCPMC9186508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.