ArticleJournal of cardiothoracic surgery2021
Dual-layer spectral detector CT to study the correlation between pericoronary adipose tissue and coronary artery stenosis.
Article in Journal of cardiothoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Quantitative assessment of coronary peri-vascular fat attenuation index using dual-layer spectral CT for differentiating high-risk plaques in coronary artery disease.BMC medical imaging · 2026Article
- Machine learning-based radiomic features of perivascular adipose tissue in coronary computed tomography angiography predicting inflammation status around atherosclerotic plaque: a retrospective cohort study.Annals of medicine · 2025Article
- Development of a new threshold for pericoronary fat attenuation based on 40 keV virtual monoenergetic images from dual-energy spectral CT.Frontiers in cardiovascular medicine · 2025Article
- Epicardial fat density obtained with computed tomography imaging - more important than volume?Cardiovascular diabetology · 2024Review
- A cloud-based medical device for predicting cardiac risk in suspected coronary artery disease: a rapid review and conceptual economic model.Health technology assessment (Winchester, England) · 2024Review
- Application of Dual-Layer Spectral-Detector Computed Tomography Angiography in Identifying Symptomatic Carotid Atherosclerosis: A Prospective Observational Study.Journal of the American Heart Association · 2024Observational
- Quantification of epicardial fat volume using low-dose cardiac scan in patients with low calcium score.Quantitative imaging in medicine and surgery · 2023Article
- Evaluation of pericoronary adipose tissue attenuation on CT.The British journal of radiology · 2023Review
- The correlation of pericoronary adipose tissue with coronary artery disease and left ventricular function.BMC cardiovascular disorders · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundTo investigate the relationship of pericoronary adipose tissue (PCAT) with coronary artery stenosis using dual-layer spectral detector CT (SDCT).
methods99 patients were retrospectively divided into normal group, non-significant stenosis group and significant stenosis group (n = 33 in each group). Fat attenuation index (FAI) 40kev, spectral curve slope (λHU), effective atomic number (Eff-Z) and epicardial fat volume (EFV) were quantitatively evaluated of the narrowest part of the lesion tissue by SDCT.
resultsThere were significant differences in PCAT parameters on SDCT (FAI40keV, λHU, Eff-Z and EFV) among the three groups (P < 0.05). FAI40keV, λHU, and Eff-Z in significant stenosis group were statistically different from those in normal group and non-significant stenosis group (P < 0.05). FAI40keV, λHU, and Eff-Z in non-significant stenosis group were statistically different from significant stenosis group (P < 0.05). EFV in normal group were significantly lower in non-significant stenosis group and significant stenosis group (P < 0.001). Univariate and multivariate logistic regression analyses identified FAI40keV (OR = 1.50, 95%CI 1.01 to 1.09) and λHU (OR = 6.81, 95%CI 1.87 to 24.86) as independent predictors of significant stenosis. FAI40keV and λHU had quite good discrimination, with an AUC of 0.84 and 0.80 respectively.
conclusionFAI40keV, λHU, and Eff-Z on SDCT in significant stenosis group were significantly different from normal and non-significant stenosis group while EFV in normal group were significantly different from non-significant stenosis group and significant stenosis group. FAI40kev and λHU were risk factors for significant stenosis.
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