Evidence map›Paper›PMID 34743721›Full record

Trial reportThe international journal of behavioral nutrition and physical activity2021

The impact of participant mental health on attendance and engagement in a trial of behavioural weight management programmes: secondary analysis of the WRAP randomised controlled trial.

Rebecca A Jones, Julia Mueller, Stephen J Sharp, Ann Vincent, Robbie Duschinsky, Simon J Griffin, Amy L Ahern

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The international journal of behavioral nutrition and physical activity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Adherence to Behavioral Weight Management: A Scoping Review of Definitions, Measurement, and Components.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Article
  9. Observational
  10. What patient-specific factors can potentially affect physiotherapy attendance of patients with knee OA at a local hospital in Singapore?Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2025
    Article
  11. Article
  12. Review
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  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rebecca A JonesMRC Epidemiology Unit, University of Cambridge, Cambridge, UK. rj397@cam.ac.uk.ORCID 0000-0003-2197-1175
Julia MuellerMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Stephen J SharpMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Ann VincentDepartment of Medicine, University College London, London, UK.
Robbie DuschinskyPrimary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Simon J GriffinMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Amy L AhernMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
University of Cambridge · GBUniversity College London · GB

Funding

Medical Research Council MC_EX_MR/J000493/1Medical Research Council MC_UU_00006/6Medical Research Council MR/J000493
6 · The paper itself

Abstract

backgroundLow attendance and engagement in behavioural weight management trials are common. Mental health may play an important role, however previous research exploring this association is limited with inconsistent findings. We aimed to investigate whether mental health was associated with attendance and engagement in a trial of behavioural weight management programmes.

methodsThis is a secondary data analysis of the Weight loss referrals for adults in primary care (WRAP) trial, which randomised 1267 adults with overweight or obesity to brief intervention, WW (formerly Weight Watchers) for 12-weeks, or WW for 52-weeks. We used regression analyses to assess the association of baseline mental health (depression and anxiety (by Hospital Anxiety and Depression Scale), quality of life (by EQ5D), satisfaction with life (by Satisfaction with Life Questionnaire)) with programme attendance and engagement in WW groups, and trial attendance in all randomised groups.

resultsEvery one unit of baseline depression score was associated with a 1% relative reduction in rate of WW session attendance in the first 12 weeks (Incidence rate ratio [IRR] 0.99; 95% CI 0.98, 0.999). Higher baseline anxiety was associated with 4% lower odds to report high engagement with WW digital tools (Odds ratio [OR] 0.96; 95% CI 0.94, 0.99). Every one unit of global quality of life was associated with 69% lower odds of reporting high engagement with the WW mobile app (OR 0.31; 95% CI 0.15, 0.64). Greater symptoms of depression and anxiety and lower satisfaction with life at baseline were consistently associated with lower odds of attending study visits at 3-, 12-, 24-, and 60-months.

conclusionsParticipants were less likely to attend programme sessions, engage with resources, and attend study assessments when reporting poorer baseline mental health. Differences in attendance and engagement were small, however changes may still have a meaningful effect on programme effectiveness and trial completion. Future research should investigate strategies to maximise attendance and engagement in those reporting poorer mental health.

trial registrationThe original trial ( ISRCTN82857232 ) and five year follow up ( ISRCTN64986150 ) were prospectively registered with Current Controlled Trials on 15/10/2012 and 01/02/2018.

Indexed as

Weight Reduction ProgramsAdultCost-Benefit AnalysisHumansMental HealthQuality of LifeSurveys and QuestionnairesWeight LossEngagementMental healthObesityPreventionWeight loss

Identifiers

PMID34743721
PMCPMC8574009
OpenAlexW3213029313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.