Evidence map›Paper›PMID 34743567›Full record

ArticleJournal of the American Heart Association2021

Pathways by Which Food Insecurity Is Associated With Atherosclerotic Cardiovascular Disease Risk.

Deepak Palakshappa, Edward H Ip, Seth A Berkowitz, Alain G Bertoni, Kristie L Foley, David P Miller, Mara Z Vitolins, Gary E Rosenthal

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Heterogeneity in associations between food insecurity and diabetes outcomes.Journal of epidemiology and community health · 2025
    Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Deepak PalakshappaDepartment of Internal Medicine Wake Forest School of Medicine Winston-Salem NC.ORCID 0000-0003-1467-4965
Edward H IpDivision of Public Health Sciences Wake Forest School of Medicine Winston-Salem NC.ORCID 0000-0002-4811-4205
Seth A BerkowitzDivision of General Medicine and Clinical Epidemiology Department of Medicine University of North Carolina at Chapel Hill School of Medicine Chapel Hill NC.ORCID 0000-0003-1030-4297
Alain G BertoniDepartment of Internal Medicine Wake Forest School of Medicine Winston-Salem NC.
Kristie L FoleyDivision of Public Health Sciences Wake Forest School of Medicine Winston-Salem NC.
David P MillerDepartment of Internal Medicine Wake Forest School of Medicine Winston-Salem NC.ORCID 0000-0001-7879-4427
Mara Z VitolinsDivision of Public Health Sciences Wake Forest School of Medicine Winston-Salem NC.
Gary E RosenthalDepartment of Internal Medicine Wake Forest School of Medicine Winston-Salem NC.
Wake Forest University · USUniversity of North Carolina at Chapel Hill · US

Funding

Understanding & Overcoming Food Insecurity in Diabetes PatientsK23DK109200 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BERKOWITZ, SETH A · 2016 to 2020
$973k
Mobile Technology for Primary Care to Address Food Insecurity and Improve Cardiovascular HealthK23HL146902 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PALAKSHAPPA, DEEPAK · 2020 to 2024
$776k
NHLBI NIH HHS K23 HL146902NIDDK NIH HHS K23 DK109200
6 · The paper itself

Abstract

Background Food insecurity (FI) has been associated with an increased atherosclerotic cardiovascular disease (ASCVD) risk; however, the pathways by which FI leads to worse cardiovascular health are unknown. We tested the hypothesis that FI is associated with ASCVD risk through nutritional/anthropometric (eg, worse diet quality and increased weight), psychological/mental health (eg, increased depressive symptoms and risk of substance abuse), and access to care pathways. Methods and Results We conducted a cross-sectional study of adults (aged 40-79 years) using the 2007 to 2016 National Health and Nutrition Examination Survey. Our primary exposure was household FI, and our outcome was 10-year ASCVD risk categorized as low (<5%), borderline (≥5% -<7.5%), intermediate (≥7.5%-<20%), and high risk (≥20%). We used structural equation modeling to evaluate the pathways and multiple mediation analysis to determine direct and indirect effects. Of the 12 429 participants, 2231 (18.0%) reported living in a food-insecure household; 5326 (42.9%) had a low ASCVD risk score, 1402 (11.3%) borderline, 3606 (29.0%) intermediate, and 2095 (16.9%) had a high-risk score. In structural models, we found significant path coefficients between FI and the nutrition/anthropometric (β, 0.130; SE, 0.027;

Indexed as

AtherosclerosisCardiovascular DiseasesAdultAgedCross-Sectional StudiesFood InsecurityFood SupplyHumansMiddle AgedNutrition SurveysRisk Factorsatherosclerotic cardiovascular diseasefood insecuritysocial determinants of health

Identifiers

PMID34743567
PMCPMC8751929
OpenAlexW3213399769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.