Evidence map›Paper›PMID 34743564›Full record

ArticleJournal of the American Heart Association2021

Sex Differences in Cardiovascular Outcomes of Older Adults After Myocardial Infarction.

Anne M Kerola, Antti Palomäki, Päivi Rautava, Maria Nuotio, Ville Kytö

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anne M KerolaDepartment of Internal Medicine Päijät-Häme Joint Authority for Health and Wellbeing Lahti Finland.ORCID 0000-0003-2257-3291
Antti PalomäkiCentre for Rheumatology and Clinical Immunology Division of Medicine Turku University Hospital Turku Finland.ORCID 0000-0002-8835-8116
Päivi RautavaDepartment of Public Health University of Turku Turku Finland.ORCID 0000-0003-2795-1327
Maria NuotioResearch Services and Department of Clinical Medicine Turku University Hospital Turku Finland.ORCID 0000-0001-8050-6084
Ville KytöHeart Center Turku University Hospital and University of Turku Turku Finland.ORCID 0000-0002-4521-1093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Evidence on the impact of sex on prognoses after myocardial infarction (MI) among older adults is limited. We evaluated sex differences in long-term cardiovascular outcomes after MI in older adults. Methods and Results All patients with MI ≥70 years admitted to 20 Finnish hospitals during a 10-year period and discharged alive were studied retrospectively using a combination of national registries (n=31 578, 51% men, mean age 79). The primary outcome was combined major adverse cardiovascular event within 10-year follow-up. Sex differences in baseline features were equalized using inverse probability weighting adjustment. Women were older, with different comorbidity profiles and rarer ST-segment-elevation MI and revascularization, compared with men. Adenosine diphosphate inhibitors, anticoagulation, statins, and high-dose statins were more frequently used by men, and renin-angiotensin-aldosterone inhibitors and beta blockers by women. After balancing these differences by inverse probability weighting, the cumulative 10-year incidence of major adverse cardiovascular events was 67.7% in men, 62.0% in women (hazard ratio [HR], 1.17; CI, 1.13-1.21;

Indexed as

Health Status DisparitiesMyocardial InfarctionAgedFemaleFinlandHumansMaleRegistriesRetrospective StudiesSex FactorsTreatment Outcomecohort studycoronary artery diseasegender differencesmyocardial infarctionoutcomes

Identifiers

PMID34743564
PMCPMC9075375

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.