Evidence map›Paper›PMID 34743551›Full record

ArticleJournal of the American Heart Association2021

Transesophageal Echocardiography in Ischemic Stroke With Atrial Fibrillation.

Kanta Tanaka, Masatoshi Koga, Keon-Joo Lee, Beom Joon Kim, Tadataka Mizoguchi, Eun Lyeong Park, Juneyoung Lee, Sohei Yoshimura, Jae-Kwan Cha, Byung-Chul Lee and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. The Integral Role of Cardiac Imaging in the Electrophysiology Field.The Journal of innovations in cardiac rhythm management · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Echocardiography in cardioembolic stroke prevention.European heart journal supplements : journal of the European Society of Cardiology · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Kanta TanakaDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center Suita Japan.ORCID 0000-0002-3291-5083
Masatoshi KogaDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center Suita Japan.ORCID 0000-0002-6758-4026
Keon-Joo LeeDepartment of Neurology Cerebrovascular Center Seoul National University Bundang Hospital Seongnam-si South Korea.ORCID 0000-0002-6571-7091
Beom Joon KimDepartment of Neurology Cerebrovascular Center Seoul National University Bundang Hospital Seongnam-si South Korea.ORCID 0000-0002-2719-3012
Tadataka MizoguchiDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center Suita Japan.
Eun Lyeong ParkDepartment of Biostatistics College of Medicine Korea University Seoul South Korea.
Juneyoung LeeDepartment of Biostatistics College of Medicine Korea University Seoul South Korea.ORCID 0000-0001-8073-9304
Sohei YoshimuraDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center Suita Japan.
Jae-Kwan ChaDepartment of Neurology Dong-A University Hospital Busan Korea.
Byung-Chul LeeDepartment of Neurology Hallym University Sacred Heart Hospital Anyang Korea.ORCID 0000-0002-3885-981X
Junpei KogeDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center Suita Japan.
Hee-Joon BaeDepartment of Neurology Cerebrovascular Center Seoul National University Bundang Hospital Seongnam-si South Korea.ORCID 0000-0003-0051-1997
Kazunori ToyodaDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center Suita Japan.ORCID 0000-0002-8346-9845
CRCS‐K Investigators, the SAMURAI Study Investigators
National Cerebral and Cardiovascular Center · JPSeoul National University Bundang Hospital · KRKorea University · KRDong-A University Hospital · KRHallym University Sacred Heart Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background To clarify differences in clinical significance of intracardiac thrombi in nonvalvular atrial fibrillation-associated stroke as identified by transesophageal echocardiography (TEE) and transthoracic echocardiography (TTE). Methods and Results Using patient data on nonvalvular atrial fibrillation-associated ischemic stroke between 2011 and 2014 from 15 South Korean stroke centers (n=4841) and 18 Japanese centers (n=1192), implementation rates of TEE/TTE, and detection rates of intracardiac thrombi at each center were correlated. The primary outcome was recurrent ischemic stroke at 1 year after the onset. A total of 5648 patients (median age, 75 years; 2650 women) were analyzed. Intracardiac thrombi were detected in 75 patients (1.3%) overall. Thrombi were detected in 7.8% of patients with TEE (either TEE alone or TEE+TTE: n=679) and in 0.6% of those with TTE alone (n=3572). Thrombus detection rates varied between 0% and 14.3% among centers. As TEE implementation rates at each center increased from 0% to 56.7%, thrombus detection rates increased linearly (detection rate [%]=0.11×TEE rate [%]+1.09 [linear regression],

Indexed as

Atrial FibrillationBrain IschemiaIschemic StrokeStrokeThrombosisAgedAtrial AppendageEchocardiography, TransesophagealFemaleHumansMaleatrial fibrillationechocardiographystroke

Identifiers

PMID34743551
PMCPMC8751927
OpenAlexW3212442384

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.