Evidence map›Paper›PMID 34742286›Full record

ArticleBMC public health2021

Predictors of late presentation and advanced HIV disease among people living with HIV in Oman (2000-2019).

Ali Elgalib, Samir Shah, Adil Al-Wahaibi, Zeyana Al-Habsi, Maha Al-Fouri, Richard Lau, Hanan Al-Kindi, Bader Al-Rawahi, Seif Al-Abri

Abstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ali ElgalibDirectorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman. alielgalib@yahoo.co.uk.ORCID 0000-0001-9245-025X
Samir ShahDirectorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.
Adil Al-WahaibiDirectorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.
Zeyana Al-HabsiDirectorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.
Maha Al-FouriDirectorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.
Richard LauDirectorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.
Hanan Al-KindiDirectorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.
Bader Al-RawahiDirectorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.
Seif Al-AbriDirectorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to determine the proportions and predictors of late presentation (LP) and advanced HIV disease (AD) in Oman. LP and AD were defined as presenting with a baseline CD4 count of < 350 and < 200 cells/mm3, respectively.

methodsWe conducted a retrospective database analysis of the National HIV Surveillance System to identify Omani people (≥ 13 years old) who were diagnosed with HIV in the period between January 2000 and December 2019 and had a documented baseline CD4 cell count. We calculated the rates and trend over time of LP and AD. A logistic regression was carried out to determine the predictors of LP and AD.

resultsA total of 1418 patients, who were diagnosed with HIV in the period from January 2000 to December 2019, were included; 71% were male and 66% were heterosexuals. The median (IQR) age at diagnosis was 33 (25-39) years. Overall, 71% (95% CI: 68-73) and 46% (95% CI: 44-49) of patients had LP and AD at presentation, respectively. The LP percentage decreased from 76% in 2000-2004 to 69% in 2015-2019; AD percentage decreased from 57 to 46% over the same period. The proportions of men with LP and AD were higher than women (74% vs. 62 and 50% vs. 36%, respectively). The percentages of persons with LP among people aged 13-24, 25-49, and ≥ 50 years were 65, 71, and 84%, respectively. The proportions of persons with AD among people aged 13-24, 25-49, and ≥ 50 years were 39, 46, and 65%, respectively. Logistic regression showed that male sex, older age, having an "unknown" HIV risk factor, and living outside Muscat were independent predictors of AD. Male sex also independently predicted LP.

conclusionsThis analysis indicates that a significant proportion of new HIV cases in Oman continue to present late. This study identified patient subgroups at greatest risk of late HIV diagnosis such as men and older people. Targeted interventions and greater efforts to scale up HIV testing services in Oman are needed.

Indexed as

HIV InfectionsAdolescentAgedCD4 Lymphocyte CountDelayed DiagnosisFemaleHumansMaleOmanRetrospective StudiesRisk FactorsAdvanced HIVHIV/AIDSLate presentationOmanPredictors

Identifiers

PMID34742286
PMCPMC8572420

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.