Evidence map›Paper›PMID 34742280›Full record

ArticleBMC cancer2021

Lymph node ratio as a predictor for minor salivary gland cancer in head and neck.

Hidenori Suzuki, Eiichi Sasaki, Gaku Takano, Seiya Goto, Daisuke Nishikawa, Shintaro Beppu, Hoshino Terada, Michi Sawabe, Nobuhiro Hanai

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hidenori SuzukiDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Aichi, 464-8681, Japan. hi.suzuki@aichi-cc.jp.ORCID http://orcid.org/0000-0002-7550-6423
Eiichi SasakiDepartment of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan.
Gaku TakanoDepartment of Otolaryngology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Japan.
Seiya GotoDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Aichi, 464-8681, Japan.
Daisuke NishikawaDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Aichi, 464-8681, Japan.
Shintaro BeppuDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Aichi, 464-8681, Japan.
Hoshino TeradaDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Aichi, 464-8681, Japan.
Michi SawabeDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Aichi, 464-8681, Japan.
Nobuhiro HanaiDepartment of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Aichi, 464-8681, Japan.
Aichi Cancer Center · JPNagoya City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigate whether pathological continuous variables of lymph nodes were related with survival results of carcinomas of minor salivary gland carcinoma in head and neck.

methodsForty-four cases with minor salivary gland carcinoma who underwent both primary resection and neck dissection were retrospectively enrolled. The pathological continuous variables were evaluated by the number of positive lymph nodes, lymph node ratio, and log odds of positive lymph nodes. Receiver operating curve analysis was used for the cut-off values of the carcinoma-specific death. Log-rank test and Cox's proportional hazards model were used for uni-/multi-variate survival analyses adjusting for pathological stage, respectively.

resultsLymph node ratio = 0.05 as well as log odds of positive lymph nodes = - 2.73 predicted the carcinoma-specific death. Both lymph node ratio and log odds of positive lymph nodes were significantly related with survival outcomes by the univariate analysis. Lymph node ratio ≥ 0.05 was associated with shorter disease-specific (hazard ratio = 7.90, 95% confidence interval = 1.54-57.1), disease-free (hazard ratio = 4.15, 95% confidence interval = 1.48-11.2) and overall (hazard ratio = 4.84, 95% confidence interval = 1.05-24.8) survival in the multivariate analysis.

conclusionA higher lymph node ratio of minor salivary gland carcinoma is a predictor of shorter survival results.

Indexed as

Lymph Node RatioConfidence IntervalsFemaleHumansLymph NodesMaleMiddle AgedNeck DissectionProportional Hazards ModelsRetrospective StudiesROC CurveSalivary Gland NeoplasmsSalivary Glands, MinorSurvival AnalysisLog odds of positive lymph nodesLymph node ratioMinor salivary gland carcinomaOverall survival

Identifiers

PMID34742280
PMCPMC8572450
OpenAlexW3214114808

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.