Evidence map›Paper›PMID 34741579›Full record

Observational studyPediatric pulmonology2022

Severe respiratory viral infections in children with history of asymptomatic or mild COVID-19.

Nooralam Rai, Joseph A Cornett, Philip Zachariah, Lynne Quittell, Stephanie Lovinsky-Desir

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nooralam RaiDivision of Pediatric Pulmonary, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.ORCID http://orcid.org/0000-0002-4796-9009
Joseph A CornettVagelos College of Physicians and Surgeons, Columbia University, 630 W 168th street, New York, New York, USA.
Philip ZachariahDivision of Pediatric Infectious Diseases, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Lynne QuittellDivision of Pediatric Pulmonary, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Stephanie Lovinsky-DesirDivision of Pediatric Pulmonary, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.ORCID https://orcid.org/0000-0003-2272-4387
Columbia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceThe spectrum of complications of COVID-19 in children, including the effect of COVID-19 on later viral infection, is not known.

objectiveTo examine the features of children hospitalized for respiratory illness with history of prior COVID-19.

designRetrospective observational case series at a single pediatric quaternary medical center in New York City. Data were obtained from review of medical records.

participantsChildren with prior mild or asymptomatic COVID-19 and no known risk factors for severe respiratory disease, who were hospitalized at our center for acute respiratory illness from October 2020 to May 2021, were reviewed. MAIN OUTCOMES AND MEASURES: Co-morbidities, history of prior COVID-19 symptoms, respiratory viral panel findings, acuity of illness, degree of respiratory decompensation based on support and interventions required, duration of hospitalization, and overall clinical course were assessed from the medical record.

resultsThis study included 5 patients (median age, 4 years; age range: 0.8-9 years; 4 [80%] male). All had positive COVID-19 serology, 1 (20%) had mild symptoms, while the others had no symptoms of prior Sars-CoV-2 infection, 3 (60%) had asthma, and the remaining had no co-morbidities. All were admitted between April and May 2021. Two were re-admitted for respiratory symptoms in the subsequent 3 months. CONCLUSIONS AND RELEVANCE: This case series describes a possible association between severe lower respiratory tract infection and prior mild COVID-19 in children. Larger cohort studies describing the respiratory effects of prior COVID-19 in children are needed.

Indexed as

COVID-19Virus DiseasesChildChild, PreschoolFemaleHospitalizationHumansInfantMaleRetrospective StudiesSARS-CoV-2asymptomaticCOVID-19lower respiratory tract infectionpediatric

Identifiers

PMID34741579
PMCPMC8661820
OpenAlexW3208747754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.