Evidence map›Paper›PMID 34741438›Full record

ArticleAutism research : official journal of the International Society for Autism Research2022

Evaluating commercially available wireless cardiovascular monitors for measuring and transmitting real-time physiological responses in children with autism.

Heather J Nuske, Matthew S Goodwin, Yelena Kushleyeva, Daniel Forsyth, Jeffrey W Pennington, Aaron J Masino, Emma Finkel, Anushua Bhattacharya, Jessica Tan, Hungtzu Tai and 3 more

Open access · greenAbstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  3. Trial
  4. Review
  5. Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Heather J NuskePenn Center for Mental Health, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-6618-3768
Matthew S GoodwinDepartment of Health Sciences, Northeastern University, Boston, Massachusetts, USA.ORCID 0000-0002-4237-601X
Yelena KushleyevaDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Daniel ForsythDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Jeffrey W PenningtonDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Aaron J MasinoResearch and Development, AiCure, New York, New York, USA.
Emma FinkelCenter for Autism Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Anushua BhattacharyaSchool of Medicine, Emory University, Atlanta, Georgia, USA.
Jessica TanPenn Center for Mental Health, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Hungtzu TaiPenn Center for Mental Health, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Zabryna Atkinson-DiazPenn Center for Mental Health, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Christopher P BonafideDivision of General Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
John D HerringtonResearch and Development, AiCure, New York, New York, USA.
Children's Hospital of Philadelphia · USPenn Center for AIDS Research · USAiCure (United States) · USEmory University · USNortheastern University · US

Funding

The Intellectual and Developmental Disabilities Research Center (IDDRC) at CHOP/PennP50HD105354 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ERIC D MARSH, ROBERT Thomas SCHULTZ · 2021 to 2026
$9.2M
The Intellectual and Developmental Disabilities Research Center at CHOP/PennU54HD086984 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI SCHULTZ, ROBERT THOMAS · 2016 to 2020
$6.3M
Reducing Challenging Behaviors In Children With Autism Through Digital HealthK01MH120509 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI NUSKE, HEATHER J · 2020 to 2024
$773k
Foerderer Grants for Excellence - Children's Hospital of Philadelphia Research InstituteMcMorris Family FoundationNICHD NIH HHS P50 HD105354NICHD NIH HHS U54 HD086984NIMH NIH HHS K01 MH120509NIMH NIH HHS K01MH120509
6 · The paper itself

Abstract

Commercially available wearable biosensors have the potential to enhance psychophysiology research and digital health technologies for autism by enabling stress or arousal monitoring in naturalistic settings. However, such monitors may not be comfortable for children with autism due to sensory sensitivities. To determine the feasibility of wearable technology in children with autism age 8-12 years, we first selected six consumer-grade wireless cardiovascular monitors and tested them during rest and movement conditions in 23 typically developing adults. Subsequently, the best performing monitors (based on data quality robustness statistics), Polar and Mio Fuse, were evaluated in 32 children with autism and 23 typically developing children during a 2-h session, including rest and mild stress-inducing tasks. Cardiovascular data were recorded simultaneously across monitors using custom software. We administered the Comfort Rating Scales to children. Although the Polar monitor was less comfortable for children with autism than typically developing children, absolute scores demonstrated that, on average, all children found each monitor comfortable. For most children, data from the Mio Fuse (96%-100%) and Polar (83%-96%) passed quality thresholds of data robustness. Moreover, in the stress relative to rest condition, heart rate increased for the Polar, F(1,53) = 135.70, p < 0.001, ηp

Indexed as

Autism Spectrum DisorderAutistic DisorderWearable Electronic DevicesAdultChildFitness TrackersHeart RateHumansautism spectrum disordercardiovascular systemfeasibility studiesheart ratephysiological stressphysiologic monitoringwearable electronic devices

Identifiers

PMID34741438
PMCPMC9040058
OpenAlexW3208902034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.