Evidence map›Paper›PMID 34741227›Full record

ArticleLung2021

Prognostic Significance of Pulmonary Artery to Aorta Ratio and Other CT Markers in Pulmonary Fibrosis With and Without Emphysema.

F Zeba, W Yanning, J Melek, F Duan, M K Atalay, M Jankowich, S Rounds

Abstract read
PubMed Publisher
In one paragraph

Article in Lung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

F ZebaPulmonary Critical Care Medicine, Dartmouth Hitchcock Medical Center, Lebanon, USA. Fatima.Zeba@hitchcock.org.ORCID 0000-0002-5356-7209
W YanningBiostatistics and Center for Statistical Sciences, School of Public Health, Brown University, Providence, USA.
J MelekHealth Informatics, Providence VA Medical Center, Providence, USA.
F DuanBiostatistics and Center for Statistical Sciences, School of Public Health, Brown University, Providence, USA.
M K AtalayDiagnostic Imaging and Cardiology, The Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, USA.
M JankowichVascular Research Laboratory, Pulmonary Critical Care Medicine, Providence VA Medical Center, The Warren Alpert Medical School of Brown University, Providence, USA.
S RoundsVascular Research Laboratory, Pulmonary Critical Care Medicine, Providence VA Medical Center, The Warren Alpert Medical School of Brown University, Providence, USA.
Brown University · USDartmouth–Hitchcock Medical Center · USProvidence VA Medical Center · US

Funding

Tracking and Evaluation CoreU54GM115677 · NIGMS · BROWN UNIVERSITY · PI ROUNDS, SHARON IRENE SMITH · 2016 to 2025
$45.0M
Uncoupling of IL-1 beta and VEGF-A Crosstalk Contributes to Impaired Arteriogenesis Response to Ischemia in Chronic Diabetes MellitusP20GM103652 · NIGMS · OCEAN STATE RESEARCH INSTITUTE, INC. · PI HARRINGTON, ELIZABETH O · 2013 to 2022
$21.3M
HDAC6 regulates cigarette smoke-induced endothelial barrier dysfunction and lung injuryR01HL130230 · NHLBI · OCEAN STATE RESEARCH INSTITUTE, INC. · PI ROUNDS, SHARON IRENE SMITH · 2016 to 2019
$1.3M
NHLBI NIH HHS R01 HL130230NIGMS NIH HHS P20 GM103652NIGMS NIH HHS U54 GM115677
6 · The paper itself

Abstract

Pulmonary hypertension (PH) is associated with decreased survival in patients with pulmonary fibrosis and combined pulmonary fibrosis and emphysema. Main pulmonary artery (PA) diameter and PA diameter/ascending aortic diameter (PA/AA) ratio, as measured on CT, have recently emerged as specific markers for PH. Our single-center retrospective study found that PA/AA ratio > 1 is associated with decreased survival in individuals with pulmonary fibrosis, with or without emphysema. Our study also describes markers of cardiac remodeling, and the echocardiographic diagnosis of PH in this patient population.

Indexed as

EmphysemaPulmonary FibrosisAortaHumansPrognosisPulmonary ArteryRetrospective StudiesTomography, X-Ray ComputedComputed tomography (CT)EmphysemaIdiopathic pulmonary fibrosisPulmonary fibrosisPulmonary hypertension

Identifiers

PMID34741227
OpenAlexW3210849044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.