Evidence map›Paper›PMID 34741202›Full record

ArticleSurgical endoscopy2022

Robotic endoscopic cooperative surgery for colorectal tumors: a feasibility study (with video).

Nariaki Okamoto, Mahdi Al-Taher, Pietro Mascagni, Alain García Vazquez, Masashi Takeuchi, Jacques Marescaux, Michele Diana, Bernard Dallemagne

Abstract readVideo-Audio Media
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Nariaki OkamotoIRCAD, Research Institute Against Digestive Cancer, 1, place de l'Hôpital, 67091, Strasbourg, France. nariaki.okamoto@ircad.fr.ORCID 0000-0002-7930-0633
Mahdi Al-TaherIRCAD, Research Institute Against Digestive Cancer, 1, place de l'Hôpital, 67091, Strasbourg, France.
Pietro MascagniFondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Alain García VazquezIHU-Strasbourg, Institute of Image-Guided Surgery, Strasbourg, France.
Masashi TakeuchiIRCAD, Research Institute Against Digestive Cancer, 1, place de l'Hôpital, 67091, Strasbourg, France.
Jacques MarescauxIRCAD, Research Institute Against Digestive Cancer, 1, place de l'Hôpital, 67091, Strasbourg, France.
Michele DianaIRCAD, Research Institute Against Digestive Cancer, 1, place de l'Hôpital, 67091, Strasbourg, France.
Bernard DallemagneIRCAD, Research Institute Against Digestive Cancer, 1, place de l'Hôpital, 67091, Strasbourg, France.
Institut de Recherche contre les Cancers de l’Appareil Digestif · FRAgostino Gemelli University Polyclinic · ITInstitut de Chirurgie Guidée par l'Image · FRKeio University · JPMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic endoscopic cooperative colorectal surgery (LECS-CR) is a promising technique to achieve full-thickness resection of colorectal tumors. This approach has shown good rates of complete resection and low local recurrence, especially for large laterally spreading tumors, which are difficult to remove via endoscopy alone. However, it is often difficult to prevent peritoneal leakage of intestinal content, causing infections and risks of cancer spreading. It was hypothesized that a robotic assistance could make the procedure easier and decrease intestinal fluid leakage. This preclinical trial aims to assess the feasibility of robotic and endoscopic cooperative colorectal surgery (RECS-CR).

methodsLECS-CR was performed in five female pigs and RECS-CR was also performed in five female pigs. With the animal under general anesthesia, pseudotumors were created on the colonic mucosa at a distance comprised between 20 and 25 cm from the anal verge. Desired resection margins were marked endoscopically and two stay sutures were placed either robotically or laparoscopically. A mucosa-to-submucosa dissection was performed endoscopically along the markings. Complete full-thickness dissection was performed cooperatively. The specimen was withdrawn endoscopically. The colon was closed using a self-fixating running suture. Abdominal contaminations, operating times, complications, and complete resections were evaluated and compared between LECS-CR and RECS-CR.

resultsThe mean number of colonies of Escherichia coli in the RECS group was significantly lower than in the LECS group (36.7 ± 30.2 vs. 142.2 ± 78.4, respectively, p < 0.05). Operating time was comparable (118 ± 11.2 vs. 98.6 ± 25.7, respectively, p = 0.22). Two stenoses occurred in the LECS group. R0 resection was achieved in all cases.

conclusionThis study suggests that RECS-CR is feasible and has the potential to reduce intestinal content leakage, potentially preventing postoperative infections.

Indexed as

Colorectal NeoplasmsLaparoscopyRobotic Surgical ProceduresAnimalsFeasibility StudiesFemaleSwineTreatment OutcomeEndoscopic submucosal dissectionFull-thickness resection of colorectal tumorsLaparoscopic endoscopic cooperative surgeryRobotic and endoscopic cooperative colorectal surgeryRobotic endoscopic cooperative surgeryRobotic surgery

Identifiers

PMID34741202
OpenAlexW3211327769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.