Evidence map›Paper›PMID 34741096›Full record

ArticleBone marrow transplantation2022

Long-term survival with mixed chimerism in patients with AML and MDS transplanted after conditioning with targeted busulfan, fludarabine, and thymoglobulin.

Albert C Yeh, Paul V O'Donnell, Gary Schoch, Paul J Martin, Chris McFarland, Jeannine S McCune, Jason P Cooper, Kris Doney, Mary E D Flowers, Mohamed L Sorror and 4 more

Open access · greenAbstract read
In one paragraph

Article in Bone marrow transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Albert C YehClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-3455-7360
Paul V O'DonnellMassachussetts General Hospital, Boston, MA, USA.
Gary SchochClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Paul J MartinClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-9051-1215
Chris McFarlandSeattle Cancer Care Alliance, Seattle, WA, USA.
Jeannine S McCuneCity of Hope Medical Center, Duarte, CA, USA.ORCID http://orcid.org/0000-0002-0795-497X
Jason P CooperDepartment of Medicine, University of Washington, Seattle, WA, USA.
Kris DoneyClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Mary E D FlowersClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Mohamed L SorrorClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Frederick R AppelbaumClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Barry E StorerClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Ted GooleyClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
H Joachim DeegClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. jdeeg@fredhutch.org.ORCID http://orcid.org/0000-0002-4426-9023
University of Washington · USCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZACity Of Hope National Medical Center · USFred Hutch Cancer Center · USMassachusetts General Hospital · USSeattle Cancer Care Alliance · US

Funding

VIRUS-MEDIATED MYELOSUPPRESSIONP01CA018029 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI STEPHANIE J LEE · 1985 to 2026
$128.4M
TRAINING IN CANCER BIOLOGY &TRANSPLANTATIONT32CA009515 · NCI · UNIVERSITY OF WASHINGTON · PI NANCY ELLEN DAVIDSON, Effie W Petersdorf · 1985 to 2026
$16.2M
RESEARCH TRAINING IN HEMATOLOGYT32HL007093 · NHLBI · UNIVERSITY OF WASHINGTON · PI Janis L Abkowitz · 1985 to 2026
$13.9M
NCI NIH HHS P01 CA018029NCI NIH HHS T32 CA009515NHLBI NIH HHS T32 HL007093
6 · The paper itself

Abstract

We evaluated long-term outcome in 40 patients with MDS or AML, transplanted from related or unrelated donors following conditioning with targeted busulfan (Bu, over 4 days), fludarabine (Flu, 120 [n = 23] or 250 [n = 17] mg/m

Indexed as

Graft vs Host DiseaseHematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteAntilymphocyte SerumBusulfanChimerismCyclophosphamideHumansNeoplasm Recurrence, LocalTransplantation ConditioningVidarabineAntilymphocyte SerumBusulfanCyclophosphamidefludarabinethymoglobulinVidarabine

Identifiers

PMID34741096
PMCPMC9112834
OpenAlexW3210366260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.