Evidence map›Paper›PMID 34740986›Full record

ArticleJournal of neurointerventional surgery2022

Patient and aneurysm factors associated with aneurysm recanalization after coiling.

Laurent Pierot, Coralie Barbe, Aurore Thierry, Fouzi Bala, Francois Eugene, Christophe Cognard, Denis Herbreteau, Stéphane Velasco, Emmanuel Chabert, Hubert Desal and 10 more

Registry-linked trialOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of neurointerventional surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01942512 (Evaluation of Risk Factors Associated With Intracranial Aneurysm Recanalization After Endovascular Treatment), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01942512 completednot on this map

Evaluation of Risk Factors Associated With Intracranial Aneurysm Recanalization After Endovascular Treatment

TypeobservationalSponsorCHU de ReimsRan2013 to 2019Enrolled1,275ConditionsIntracranial AneurysmArmsEndovascular treatment of intracranial aneurysm
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  11. Balloon inflation predicts recanalization of intracranial aneurysms treated with coiling alone.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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  14. Observational
  15. Interdependence of First-coil and Global volume embolization ratios (VERs) calculated by Sim&Size in predicting aneurysm occlusion outcomes.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 18 institutions in 4 countries.

Laurent PierotRadiology, CHU Reims, Reims, France lpierot@gmail.com.ORCID http://orcid.org/0000-0002-6893-661X
Coralie BarbeResearch on Health University department, University of Reims Champagne-Ardenne, Reims, France.
Aurore ThierryCHU Reims, Reims, France.
Fouzi BalaClinical Neurosciences, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
Francois EugeneRadiologie, CHU Rennes, Rennes, France.ORCID http://orcid.org/0000-0001-7367-8793
Christophe CognardDiagnostic and Therapeutic Neuroradiology, CHU Toulouse, Toulouse, Occitanie, France.
Denis HerbreteauNRI, CHU Tours, Tours, France.
Stéphane VelascoRadiology, CHU Poitiers, Poitiers, France.
Emmanuel ChabertNeuroradiologie, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France.
Hubert DesalNeuroradiology, CHU Nantes, Nantes, France.
Mohamed AggourNeuroradiology, CHU Saint-Étienne, Saint-Etienne, France.
Christine Rodriguez-RegentRadiology, Centre Hospitalier Sainte Anne, Paris, France.
Sophie GallasDiagnostic and Interventional Neuroradiology, Hopital Bicetre, Le Kremlin-Bicetre, France.
Jacques SedatRadiology, CHU Nice, Nice, France.ORCID http://orcid.org/0000-0003-2312-1457
Gaultier MarnatInterventional and Diagnostic Neuroradiology, CHU Bordeaux GH Pellegrin, Bordeaux, France.ORCID http://orcid.org/0000-0002-7611-7753
Nader SourourNeuroradiology, APHP, Paris, France.
Arturo ConsoliDiagnostic and Interventional Neuroradiology, Hospital Foch, Suresnes, France.ORCID http://orcid.org/0000-0001-6640-8541
Chrysanthi PapagiannakiInterventional Neuroradiology, CHU Rouen, Rouen, France.ORCID http://orcid.org/0000-0002-9473-9644
Laurent SpelleNEURI Interventional Neuroradiology, APHP, Paris, France.ORCID http://orcid.org/0000-0002-6748-8528
Phil WhiteInstitute for Ageing & Health, Newcastle University, Newcastle Upon Tyne, UK.
Centre Hospitalier Universitaire de Reims · FRAssistance Publique – Hôpitaux de Paris · FRAzienda Ospedaliero-Universitaria Careggi · ITBicêtre Hospital · FRCentre Hospitalier Sainte-Anne · FRCentre Hospitalier Universitaire de Clermont-Ferrand · FRCentre Hospitalier Universitaire de Nantes · FRCentre Hospitalier Universitaire de Nice · FRCentre Hospitalier Universitaire de Poitiers · FRCentre Hospitalier Universitaire de Rennes · FRCentre Hospitalier Universitaire de Rouen · FRCentre Hospitalier Universitaire de Saint-Étienne · FRCentre Hospitalier Universitaire de Tours · FRHôpital Pellegrin · FRNewcastle upon Tyne Hospitals NHS Foundation Trust · GBUniversité de Reims Champagne-Ardenne · FRUniversité Paris-Saclay · FRUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne limitation of the endovascular treatment of intracranial aneurysms is aneurysm recanalization. The Analysis of Recanalization after Endovascular Treatment of intracranial Aneurysm (ARETA) study is a prospective multicenter cohort study evaluating the factors associated with recanalization after endovascular treatment.

methodsThe current analysis is focused on patients treated by coiling or balloon-assisted coiling (BAC). Postoperative, mid-term vascular imaging, and evolution of aneurysm occlusion were independently evaluated by two neuroradiologists. A 3-grade scale was used for aneurysm occlusion (complete occlusion, neck remnant, and aneurysm remnant) and for occlusion evolution (improved, stable, and worsened). Recanalization was defined as any worsening of aneurysm occlusion.

resultsBetween December 2013 and May 2015, 16 French neurointerventional departments enrolled 1289 patients. A total of 945 aneurysms in 908 patients were treated with coiling or BAC. The overall rate of aneurysm recanalization at mid-term follow-up was 29.5% (95% CI 26.6% to 32.4%): 28.9% and 30.3% in the coiling and BAC groups, respectively. In multivariate analyses factors independently associated with recanalization were current smoking (36.6% in current smokers vs 24.5% in current non-smokers (OR 1.8 (95% CI 1.3 to 2.4); p=0.0001), ruptured status (31.9% in ruptured aneurysms vs 25.1% in unruptured (OR 1.5 (95% CI 1.1 to 2.1); p=0.006), aneurysm size ≥10 mm (48.8% vs 26.5% in aneurysms <10 mm (OR 2.6 (95% CI 1.8 to 3.9); p<0.0001), wide neck (32.1% vs 25.8% in narrow neck (OR 1.5 (95% CI 1.1 to 2.1); p=0.02), and MCA location (34.3% vs 28.3% in other locations (OR 1.5 (95% CI 1.0 to 2.1); p=0.04).

conclusionsSeveral factors are identified by the ARETA study as playing a role in aneurysm recanalization after coiling: current smoking, aneurysm status (ruptured), aneurysm size (≥10 mm), neck size (wide neck), and aneurysm location (middle cerebral artery). This finding has important consequences in clinical practice. TRIAL REGISTRATION NUMBER: URL: http://www. CLINICALTRIALS: gov; Unique Identifier: NCT01942512.

Indexed as

Aneurysm, RupturedEmbolization, TherapeuticEndovascular ProceduresIntracranial AneurysmVascular DiseasesCohort StudiesFollow-Up StudiesHumansProspective StudiesRetrospective StudiesStentsTreatment Outcomeaneurysm

Identifiers

PMID34740986
PMCPMC9606530
OpenAlexW3209243040

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.