Evidence map›Paper›PMID 34740892›Full record

ArticleCancer research2022

Loss of Long Noncoding RNA

Ruchi Ghildiyal, Mithila Sawant, Arun Renganathan, Kiran Mahajan, Eric H Kim, Jingqin Luo, Ha X Dang, Christopher A Maher, Felix Y Feng, Nupam P Mahajan

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
7.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Review
  3. [Targeting chimera technology: A new tool for undruggable in breast cancer].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  4. Article
  5. Review
  6. Androgen Signaling in Prostate Cancer: When a Friend Turns Foe.Endocrine, metabolic & immune disorders drug targets · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ruchi Ghildiyal *Department of Surgery, Washington University in St. Louis, St. Louis, Missouri.
Mithila Sawant *Department of Surgery, Washington University in St. Louis, St. Louis, Missouri.
Arun RenganathanDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri.ORCID 0000-0002-6722-8136
Kiran MahajanDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri.
Eric H KimDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri.
Jingqin LuoSiteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri.ORCID 0000-0003-2759-3072
Ha X DangDepartment of Biomedical Engineering, McDonnell Genome Institute, Washington University in St. Louis, St. Louis, Missouri.
Christopher A MaherSiteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri.
Felix Y FengHelen Diller Family Cancer Research Building, University of California, San Francisco, California.
Nupam P MahajanDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri. nupam@wustl.edu.
Washington University in St. Louis · USJames S. McDonnell Foundation · USUCSF Helen Diller Family Comprehensive Cancer Center · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
Molecular Mechanisms of Castration Resistant Prostate Cancer Recurrence & Therapeutic StrategiesR01CA227025 · NCI · WASHINGTON UNIVERSITY · PI FENG, FELIX YI-CHUNG, MAHAJAN, NUPAM P · 2019 to 2023
$2.8M
Targeting a Novel Epigenetic Signaling Nexus ACK1-pY88H4-AR/AR-V7 in Drug Resistant Metastatic Prostate CancerR01CA208258 · NCI · WASHINGTON UNIVERSITY · PI MAHAJAN, NUPAM P · 2017 to 2021
$1.7M
NCI NIH HHS P30 CA091842NCI NIH HHS R01 CA208258NCI NIH HHS R01 CA227025
6 · The paper itself

Abstract

Androgen receptor (AR) signaling continues to play a dominant role in all stages of prostate cancer, including castration-resistant prostate cancers (CRPC) that have developed resistance to second generation AR antagonists such as enzalutamide. In this study, we identified a long noncoding RNA (lncRNA),

Indexed as

AnimalsBenzamidesDrug Resistance, NeoplasmHumansMaleMiceMice, SCIDNitrilesPhenylthiohydantoinProstatic Neoplasms, Castration-ResistantReceptors, AndrogenRNA, Long NoncodingTransfectionBenzamidesenzalutamideNitrilesPhenylthiohydantoinReceptors, AndrogenRNA, Long Noncoding

Identifiers

PMID34740892
PMCPMC8732311
OpenAlexW3209117101

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.