Evidence map›Paper›PMID 34740640›Full record

ArticleThe Science of the total environment2022

Profiles of primary aromatic amines, nicotine, and cotinine in indoor dust and associated human exposure in China.

Sridhar Chinthakindi, Qingqing Zhu, Chunyang Liao, Kurunthachalam Kannan

Abstract read
In one paragraph

Article in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Tracking Aromatic Amines from Sources to Surface Waters.Environmental science & technology letters · 2024
    Review
  3. Article
  4. Article
  5. Variability in urinary concentrations of primary aromatic amines.The Science of the total environment · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sridhar ChinthakindiDepartment of Pediatrics and Department of Environmental Medicine, New York University School of Medicine, New York, NY 10016, United States.
Qingqing ZhuState Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Chunyang LiaoState Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Kurunthachalam KannanDepartment of Pediatrics and Department of Environmental Medicine, New York University School of Medicine, New York, NY 10016, United States; Biochemistry Department, Faculty of Science and Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: Kurunthachalam.kannan@nyulangone.org.

Funding

Wadsworth Center's Human Health and Exposure Analysis Resource (WC-HHEAR)U2CES026542 · NIEHS · WADSWORTH CENTER · PI KANNAN, KURUNTHACHALAM, KANNAN, KURUNTHACHALAM · 2015 to 2025
$15.6M
NIEHS NIH HHS U2C ES026542
6 · The paper itself

Abstract

Despite the widespread use of primary aromatic amines (AAs) in consumer products, little is known about their prevalence in house dust. In this study, we investigated the occurrence of 35 AAs and two tobacco chemical markers (nicotine and its breakdown product cotinine) in 119 samples of house dust collected from five provinces in China. Ten of the 35 AAs and [nicotine and cotinine] were found in >80% and 100% of the samples, respectively, at concentration ranges of 29.1-19,200 (median: 700 ng/g) and 23.2-22,400 (4600) ng/g, respectively. Aniline was the predominant AA found in all dust samples (median: 257 ng/g). Dust samples from Henan and Shanxi provinces contained higher summed concentrations of the 10 AAs than those from Sichuan and Shandong, although the concentrations did not vary significantly among the five provinces (p > 0.05). A significant (p = 0.048), positive correlation (r = 0.882) existed between concentrations of nicotine and cotinine in dust samples. Similarly, concentrations of AAs were significantly correlated with those of nicotine in dust samples. Dyestuffs, rubber products, polyurethane foam and tobacco smoke are the major sources of AAs in the indoor environment. The estimated daily intakes (EDI) through dust ingestion ranged from 0.349 (adults) to 6.62 ng/kg-bw/day (toddlers) for AAs and from 1.27 to 51.1 ng/kg-bw/day for nicotine which are well below the current tolerable daily intakes.

Indexed as

Air Pollution, IndoorCotinineAdultAminesChinaDustEnvironmental ExposureHumansNicotineAminesCotinineDustNicotineAnilineAromatic aminesChinaIndoor dustLC-MS/MSNicotine

Identifiers

PMID34740640
PMCPMC8639806

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.