ArticleAmerican journal of ophthalmology2022
Optic Disc Microvasculature Dropout in Glaucoma Detected by Swept-Source Optical Coherence Tomography Angiography.
Article in American journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Microvascular Dropout Within the Lamina Cribrosa in Myopic Eyes With a Parapapillary γ-Zone and Primary Open-Angle Glaucoma.Investigative ophthalmology & visual science · 2026Article
- Evaluation of OCT Angiography Parameters as Biomarkers for Glaucoma Progression.Diagnostics (Basel, Switzerland) · 2025Article
- Relationship Between Parapapillary Microvasculature Dropout and Visual Field Defect in Glaucoma: A Cross-Sectional OCTA Analysis.Journal of clinical medicine · 2025Article
- Color Doppler Imaging Assessment of Ocular Blood Flow Following Ab Externo Canaloplasty in Primary Open-Angle Glaucoma.Journal of clinical medicine · 2024Article
- Research progress of optic nerve imaging during 1991-2023: a bibliometric analysis.Quantitative imaging in medicine and surgery · 2024Article
- Reduction of Optic Disc Microvasculature and Retinal Nerve Fiber Layer Thinning in Patients With Glaucoma.American journal of ophthalmology · 2024Article
- Parapapillary choroidal microvasculature dropout in eyes with primary open-angle glaucoma.Scientific reports · 2023Article
- Temporal Optic Disc Microvasculature Dropout in Glaucoma.Investigative ophthalmology & visual science · 2023Article
- Reduced intradisc vessel density is associated with optic disc hemorrhage in eyes with primary open-angle glaucoma.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
purposeTo assess the clinical utility of swept-source optical coherence tomography angiography (SS-OCTA) in detecting optic disc microvasculature dropout (MvD-D) in primary open-angle glaucoma (POAG) eyes.
designCross-sectional study.
methodsThe study enrolled 197 eyes of 197 patients with POAG with acceptable-quality SS-OCTA (PLEX Elite 9000; Carl Zeiss Meditec) images. A whole-signal-mode 6.0- × 6.0-mm optic disc cube was obtained with projection artifact removal. Three groups were categorized: no MvD-D (group 1), MvD-D (group 2, complete loss of microvasculature within the optic disc), and indiscernible MvD-D (group 3, poor visualization of the anterior lamina cribrosa [LC]).
resultsThere were 82 (42.1%) and 81 (41.5%) eyes categorized as no MvD-D (group 1) and MvD-D (group 2), respectively. The remaining 32 eyes (16.4%), categorized as indiscernible MvD-D (group 3), had a significantly smaller anterior scleral canal opening (ASCO) area (P < .05). Group 2 had significantly worse visual field (VF) mean deviation (MD), thinner average retinal nerve fiber layer (RNFL), higher prevalence of focal LC defect, and parapapillary deep-layer microvasculature dropout (MvD-P) than the other 2 groups (P < .05). In the multivariable logistic regression analysis, higher prevalence of focal LC defect (odds ratio, 46.91; P < .001) and MvD-P (odds ratio, 48.94; P < .001) remained as factors associated with MvD-D.
conclusionsThe presence of MvD-D could be well determined by SS-OCTA in eyes with POAG. MvD-P and focal LC defects were strongly associated with MvD-D. This suggests that SS-OCTA can serve as a useful tool in detecting optic disc microvasculature damage.
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