Observational studyBMC surgery2021
Postoperative complications: an observational study of trends in the United States from 2012 to 2018.
Observational study in BMC surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07464860 (A Box Breathing Intervention and the Surgical Stress Response in Older Adults Undergoing Total Knee Arthroplasty), which is not on this map. Cited by 69 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Box Breathing Intervention and the Surgical Stress Response in Older Adults Undergoing Total Knee Arthroplasty: A Randomized Controlled Feasibility Trial
Who cites it
69 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Potential role of breast MRI to identify patients with high-risk lesions who might avoid surgery: a systematic review and meta-analysis.European radiology · 2026Pooled it
- Predictive accuracy of surgeon gestalt for adverse postoperative outcomes: systematic review.The British journal of surgery · 2025Pooled it
- Prediction of Complications and Prognostication in Perioperative Medicine: A Systematic Review and PROBAST Assessment of Machine Learning Tools.Anesthesiology · 2024Pooled it
- Incidence and predictors of postoperative complications in Sub-Saharan Africa: a systematic review and meta-analysis.Frontiers in health services · 2024Pooled it
- Collagenase Versus Operative Management for Dupuytren Contracture: A Propensity-matched Cohort of 16,888 Patients.Plastic and reconstructive surgery. Global open · 2026Article
- Balancing Objectivity and Humanity: Ethical Challenges and Considerations in Surgical Candidacy Decisions.HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues · 2026Article
- Article
- Harmful incidents following gynaecological ambulatory surgery: A scoping review.International journal of nursing studies advances · 2026Review
- Cohort profile: PeRiOperative sTress risk assEssment and Clinical decision cohorT (PROTECT), a multi-center observational study based on real-world data.BMC geriatrics · 2026Observational
- End-of-surgery prediction of postoperative infectious complications from intraoperative vital-sign dynamics.NPJ digital medicine · 2026Article
- Clinical Characteristics, Management, and Outcomes of Intramedullary Spinal Cord Ependymomas: A Systematic Review and Meta-Analysis.Spine surgery and related research · 2026Review
- Assessment of surgical proficiency based on evaluating muscle activity, bimanual muscle coordination, and fatigue susceptibility in simulated laparoscopic tasks.Medical & biological engineering & computing · 2026Article
- High-intensity light therapy for post-interventional complications and pain after minimally invasive spinal procedures: a case series.Lasers in medical science · 2026Article
- Spatiotemporal characteristics of eye-hand coordination among different skill levels in laparoscopic surgery.Surgical endoscopy · 2026Article
- Impact of a digital pre- and rehabilitation program on postoperative outcomes after pelvic gynecological surgery.Frontiers in digital health · 2026Article
- Surgical site infections occurrence and associated risk factors: a matched case-control study.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Towards an AI-driven registry for postoperative complications: a proof-of-concept study evaluating the opportunities and challenges of AI models.BMJ health & care informatics · 2025Article
- The Impact of Multidisciplinary Preoperative Optimization Program on Postoperative Outcomes Among Surgical Oncology Patients.Journal of clinical medicine · 2025Article
- Non-β-Lactam Antibiotic Use, β-Lactam Allergy, and Surgical Site Infections.JAMA surgery · 2025Article
- Establishing anmSphere · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundPostoperative complications continue to constitute a major issue for both the healthcare system and the individual patient and are associated with inferior outcomes and higher healthcare costs. The objective of this study was to evaluate the trends of postoperative complication rates over a 7-year period.
methodsThe NSQIP datasets from 2012 to 2018 were used to assess 30-day complication incidence rates including mortality rate following surgical procedures within ten surgical subspecialties. Multivariable logistic regression was used to associate complication rates with dataset year, while adjusting for relevant confounders.
resultsA total of 5,880,829 patients undergoing major surgery were included. Particularly the incidence rates of four complications were found to be decreasing: superficial SSI (1.9 to 1.3%), deep SSI (0.6 to 0.4%), urinary tract infection (1.6 to 1.2%) and patient unplanned return to the operating room (3.1 to 2.7%). Incidence rate for organ/space SSI exhibited an increase (1.1 to 1.5%). When adjusted, regression analyses indicated decreased odds ratios (OR) through the study period years for particularly deep SSI OR 0.92 [0.92-0.93], superficial SSI OR 0.94 [0.94-0.94] and acute renal failure OR 0.96 [0.95-0.96] as the predictor variable (study year) increased (p < 0.01). However, OR's for organ/space SSI 1.05 [1.05-1.06], myocardial infarction 1.01 [1.01-1.02] and sepsis 1.01 [1.01-1.02] increased slightly over time (all p < 0.01).
conclusionsIncidence rates for the complications exhibited a stable trend over the study period, with minor in or decreases observed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.