ArticleBMC health services research2021
The impact of patient delirium in the intensive care unit: patterns of anxiety symptoms in family caregivers.
Article in BMC health services research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03379129 (Validation of Family-Administered Delirium Detection Tools for the Identification of Delirium in Critically Ill Patients), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validation of Family-Administered Delirium Detection Tools for the Identification of Delirium in Critically Ill Patients
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Components and effects of psychosocial support interventions for relatives of patients with delirium in hospitals, systematic review.BMC geriatrics · 2026Pooled it
- Family-administered delirium screening improves satisfaction among ICU caregivers: a prospective cohort study.Intensive care medicine · 2026Article
- Comparison Study of Multiple Machine Learning Models for Predicting Anxiety Among Neurosurgical ICU Family Members Using Critical Care Family Needs Inventory.Journal of nursing management · 2026Article
- Delirium in the Acute Care Setting From the Families Perspective: A Scoping Review.Journal of advanced nursing · 2026Article
- Promoting Family Involvement in the Management of Delirium in Intensive Care: Scoping Review.Medicina (Kaunas, Lithuania) · 2024Article
- The spectrum of psychological disorders in family members of patients suffering from delirium associated with critical illness: a prospective, observational study.Scientific reports · 2024Observational
- Psychological interventions for patients with delirium in intensive care: A scoping review protocol.PloS one · 2024Article
- Family experiences and attitudes toward care of ICU patients with delirium: A scoping review.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to examine the association of patient delirium in the intensive care unit (ICU) with patterns of anxiety symptoms in family caregivers when delirium was determined by clinical assessment and family-administered delirium detection.
methodsIn this cross-sectional study, consecutive adult patients anticipated to remain in the ICU for longer than 24 h were eligible for participation given at least one present family caregiver (e.g., spouse, friend) provided informed consent (to be enrolled as a dyad) and were eligible for delirium detection (i.e., Richmond Agitation-Sedation Scale score ≥ - 3). Generalized Anxiety Disorder-7 (GAD-7) was used to assess self-reported symptoms of anxiety. Clinical assessment (Confusion Assessment Method for ICU, CAM-ICU) and family-administered delirium detection (Sour Seven) were completed once daily for up to five days.
resultsWe included 147 family caregivers; the mean age was 54.3 years (standard deviation [SD] 14.3 years) and 74% (n = 129) were female. Fifty (34% [95% confidence interval [CI] 26.4-42.2]) caregivers experienced clinically significant symptoms of anxiety (median GAD-7 score 16.0 [interquartile range 6]). The most prevalent symptoms of anxiety were "Feeling nervous, anxious or on edge" (96.0% [95%CI 85.2-99.0]); "Not being able to stop or control worrying" (88.0% [95%CI 75.6-94.5]; "Worrying too much about different things" and "Feeling afraid as if something awful might happen" (84.0% [95%CI 71.0-91.8], for both). Family caregivers of critically ill adults with delirium were significantly more likely to report "Worrying too much about different things" more than half of the time (CAM-ICU, Odds Ratio [OR] 2.27 [95%CI 1.04-4.91]; Sour Seven, OR 2.28 [95%CI 1.00-5.23]).
conclusionsFamily caregivers of critically ill adults with delirium frequently experience clinically significant anxiety and are significantly more likely to report frequently worrying too much about different things. Future work is needed to develop mental health interventions for the diversity of anxiety symptoms experienced by family members of critically ill patients.
trial registrationThis study is registered on ClinicalTrials.gov ( https://clinicaltrials.gov/ct2/show/NCT03379129 ).
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