Evidence map›Paper›PMID 34740330›Full record

ArticleBMC neurology2021

Ring finger sensory latency difference in the diagnosis and treatment of carpal tunnel syndrome.

Qingping Wang, Hong Chu, Hongyang Wang, Yan Jin, Xiaoquan Zhao, Chao Weng, Zuneng Lu

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qingping Wang *Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, PR China.
Hong Chu *Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, PR China.
Hongyang WangDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, PR China.
Yan JinDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, PR China.
Xiaoquan ZhaoDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, PR China.
Chao WengDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, PR China. wengch@whu.edu.cn.
Zuneng LuDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, PR China. lzn196480@126.com.
Wuhan University · CNRenmin Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the sensitivity of median and ulnar nerve sensory latency differences in diagnosing carpal tunnel syndrome (CTS) at different severities.

methodsCTS patients were divided into three groups based on disease severity (mild, moderate, and severe). Distal latency of sensory nerve action potential (SNAP) for the median and ulnar nerves was recorded. The sensitivity of SNAP distal latency to CTS and its correlation with CTS severity were analyzed.

resultsSignificant differences were found in the median nerve sensory action potential distal latency (MSDL) and in the median and ulnar sensory latency difference to ring finger (MUD) but not in the ulnar nerve sensory action potential distal latency (USDL) between CTS and control. The sensitivity and specificity were 92.2 and 99.4% with an MSDL cutoff value of 2.40 ms, respectively, and were both 100% with a MUD cutoff value of 0.33 ms. There was no significant difference in USDL among the CTS and control groups. Significant differences were found in MSDL and MUD among the CTS severities and between mild and moderate CTS, but not between mild and severe CTS or between moderate and severe CTS. Correlations with CTS severity were observed for MSDL and MUD but not for USDL.

conclusionThe ulnar nerve of the CTS patients was not damaged. A smaller MSDL reflected median nerve damage, which can be used for the early diagnosis of CTS. MUD correlated with CTS severity with a higher sensitivity than MSDL, which can provide therapeutic insight without pain to patients.

Indexed as

Carpal Tunnel SyndromeFingersHumansMedian NerveNeural ConductionUlnar Nervecarpal tunnel syndromemedian nervenerve conduction studiessensory distal latencyulnar nerve

Identifiers

PMID34740330
PMCPMC8570028
OpenAlexW3201491690

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.