Evidence map›Paper›PMID 34740020›Full record

Trial reportDrug and alcohol dependence2021

HCV communication within ego-centric networks of men and women who inject drugs.

Marisa Felsher, Karin E Tobin, Mark Sulkowski, Carl Latkin, Oluwaseun Falade-Nwulia

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marisa FelsherJohns Hopkins University School of Medicine, Division of Infectious Diseases, 5200 Eastern Avenue, MFL Center Tower, Suite 381, Baltimore, MD 21224, USA. Electronic address: marfelsher@gmail.com.
Karin E TobinJohns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
Mark SulkowskiJohns Hopkins University School of Medicine, Division of Infectious Diseases, 5200 Eastern Avenue, MFL Center Tower, Suite 381, Baltimore, MD 21224, USA.
Carl LatkinJohns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
Oluwaseun Falade-NwuliaJohns Hopkins University School of Medicine, Division of Infectious Diseases, 5200 Eastern Avenue, MFL Center Tower, Suite 381, Baltimore, MD 21224, USA.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
The Effects of Drug Use, Depression, and Social Factors on HIV/HCV Care Continuum among PWID in Urban Areas: A Social-Network PerspectiveR01DA040488 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LATKIN, CARL A, TOBIN, KARIN E · 2015 to 2020
$4.0M
Patient Oriented Research in Hepatitis C-infected Injection Drug UsersK24DA034621 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SULKOWSKI, MARK SEBASTIAN · 2012 to 2022
$1.2M
The impact of social networks on hepatitis C transmission and care access in people who inject drugsK23DA041294 · NIDA · JOHNS HOPKINS UNIVERSITY · PI FALADE-NWULIA, OLUWASEUN · 2016 to 2020
$924k
A pilot Peer Mentor intervention that trains Black MSM to use and promote uptake of HIV/STI self-testing to peers and sex partners.R34MH118178 · NIMH · JOHNS HOPKINS UNIVERSITY · PI TOBIN, KARIN E · 2019 to 2021
$737k
NIAID NIH HHS P30 AI094189NIDA NIH HHS K23 DA041294NIDA NIH HHS K24 DA034621NIDA NIH HHS R01 DA040488NIMH NIH HHS R34 MH118178
6 · The paper itself

Abstract

introductionLeveraging interpersonal communication among social networks of people who inject drugs (PWID) may be an innovative strategy to increase awareness and access to hepatitis C (HCV) care. However, little is known about HCV communication patterns among PWID and if these patterns vary by gender.

methodsEgocentric network data collected at baseline from HCV-infected PWID enrolled in a randomized HCV treatment intervention trial in Baltimore, Maryland were analyzed. Logistic generalized estimating models were conducted to identify predictors of HCV communication.

resultsAmong 227 PWID, the mean age was 43.8 (SD=10.3), 28.2% (n = 64) were women and 71.8% (n = 163) were men. Female participants reported 516 dyadic relationships and male participants 1139 dyadic relationships. While there were significant gender differences based on socio-demographics, risk behavior and network composition, there were few differences in HCV communication patterns. Both men and women had increased odds of HCV communication with alters who are currently enrolled in drug treatment (AOR 1.7, 95% CI: 1.3-2.4), alters with whom participants share drug preparation equipment (AOR 3.0, 95% CI: 1.9-4.6), alters who are sex partners compared to kin (AOR 3.0; 95% CI: 1.9-4.9) and alters with whom respondents have increased trust (AOR 1.1; 95% CI: 1.11.2) and daily/weekly interactions (AOR 1.7; 95% CI 1.3-2.1).

conclusionPWID engaged with trusted alters about HCV disclosure and information, highlighting the important role network interventions could play in this vulnerable population.

Indexed as

Hepatitis CPharmaceutical PreparationsSubstance Abuse, IntravenousAdultCommunicationEgoFemaleHumansMalePharmaceutical PreparationsGenderHepatitis CInterpersonal communicationPeople who inject drugsSocial networks

Identifiers

PMID34740020
PMCPMC8665146
OpenAlexW3207997009

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.