Evidence map›Paper›PMID 34739763›Full record

ArticleHypertension (Dallas, Tex. : 1979)2022

Clinical Significance of Mean and Pulse Pressure in Patients With Heart Failure With Preserved Ejection Fraction.

Fang-Fei Wei, Yuzhong Wu, Ruicong Xue, Xiao Liu, Xin He, Bin Dong, Zhe Zhen, Xuwei Chen, Weihao Liang, Jingjing Zhao and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 3 countries.

Fang-Fei WeiDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).ORCID 0000-0002-4573-2403
Yuzhong WuDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).
Ruicong XueDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).
Xiao LiuDepartment of Cardiology, the Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (X.L.).
Xin HeDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).
Bin DongDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).
Zhe ZhenDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).
Xuwei ChenDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).
Weihao LiangDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).ORCID 0000-0001-9601-9184
Jingjing ZhaoDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).
Jiangui HeDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).
Yugang DongDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).
Jan A StaessenResearch Institute Alliance for the Promotion of Preventive Medicine, Mechelen, Belgium (J.A.S.).ORCID 0000-0002-3026-1637
Chen LiuDepartment of Cardiology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China (F.-F.W., Y.W., R.X., X.H., B.D., Z.Z., X.C., W.L., J.Z., J.H., Y.D., C.L.).ORCID 0000-0002-9818-0454
Sun Yat-sen University · CNSociety of General Internal Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It remains debated whether pulse pressure is associated with left ventricular traits and adverse outcomes over and beyond mean arterial pressure (MAP) in patients with heart failure (HF) with preserved ejection fraction. We investigated these associations in 3428 patients with HF with preserved ejection fraction (51.5% women; mean age, 68.6 years) enrolled in the TOPCAT trial (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist). We computed association sizes and hazards ratios with 1-SD increase in MAP and pulse pressure. In multivariable-adjusted analyses, association sizes (

Indexed as

AgedBlood PressureEchocardiographyFemaleHeart FailureHumansMaleMiddle AgedStroke Volumeblood pressureechocardiographyhealth outcomesheart failure

Identifiers

PMID34739763
PMCPMC8654124
OpenAlexW3210600684

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.