Evidence map›Paper›PMID 34739675›Full record

ArticleBiological trace element research2022

Nano-Selenium and Macleaya cordata Extracts Improved Immune Functions of Intrauterine Growth Retardation Piglets under Maternal Oxidation Stress.

Changlin Liu, Yuanfeng Li, Haiyan Li, Yachao Wang, Kui Zhao

Abstract readRandomized Controlled Trial, Veterinary
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Plant-derived polyphenols in sow nutrition: An update.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023
    Review
  12. Review
  13. Review
  14. Article
  15. Effects ofAnimals : an open access journal from MDPI · 2022
    Article
  16. Toxicological effects of nanoselenium in animals.Journal of animal science and biotechnology · 2022
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Changlin LiuCollege of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, China.
Yuanfeng LiCollege of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, China.
Haiyan LiCollege of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, China.
Yachao WangCollege of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, China. wangyachao1688@126.com.ORCID http://orcid.org/0000-0002-4401-7010
Kui ZhaoSchool of Materials and Architectural Engineering, Guizhou Normal University, Guiyang, 550025, China.
Southwest University of Science and Technology · CNGuizhou Normal University · CN

Funding

Research and Application of Key Technologies for Safe Low Excretion Feed Production in Large-scale Pig Farms 2018NZ0046
6 · The paper itself

Abstract

Intrauterine growth retardation (IUGR) is the main death cause of newborn piglets in large-scale farms. To investigate the effects of maternal nano-selenium (nano-Se) and Macleaya cordata extracts (MCE) on immune functions of IUGR piglets in large scale farms, a 2 × 2 factorial design was adopted in this test, and two factors were nano-Se (0, 0.50 mg/kg) and MCE (0, 500 mg/kg). A total of 32 ternary hybrid sows (Landrace × Yorkshire × Duroc, parity 2) were used in this 25-day trial from day 90 of pregnancy to delivery. The dietary treatments were as follows: (1) CON group, basic diet (0.0 mg/kg Se); (2) Nano-Se group, basic diet + 0.50 mg/kg added Se (nano-Se); (3) MCE group, basic diet + 500 mg/kg added MCE; (4) Combined group, basic diet + 0.50 mg/kg added nano-Se and 500 mg/kg added MCE. Maternal nano-Se or combination of nano-Se and MCE diets extremely increased the superoxide dismutase (SOD), catalase (CAT), superoxide dismutase (GSH-Px) contents in the serum and liver of IUGR offspring (P < 0.05), and MCE supplementation in sow diets remarkably increased the serum superoxide dismutase (SOD), catalase (CAT), and superoxide dismutase (GSH-Px) contents of IUGR piglets (P < 0.05). Adding nano-Se, MCE, or nano-Se and MCE to sow diets decreased the malondialdehyde (MDA) content in the serum and liver of IUGR piglets (P < 0.05). The supplementation of nano-Se and combined diets extremely increased the activities of immunoglobulin G (IgG) and immunoglobulin A (IgA) in the serum and liver of IUGR offspring (P < 0.05). Maternal nano-Se, MCE, and combined diets greatly decreased the levels of tumor necrosis factor-alpha (TNF-α), interleukin 6 (IL-6), and interleukin-1β (IL-1β) in the serum and liver of IUGR piglets (P < 0.05). Together, the application of nano-Se and/or MCE to sow diets improved antioxidant capacities and immune functions of IUGR offspring, and alleviated oxidative stress.

Indexed as

AntioxidantsFetal Growth RetardationPlant ExtractsSeleniumAnimal FeedAnimalsCatalaseDietDietary SupplementsFemaleImmunityPregnancySuperoxide DismutaseSwineAntioxidantsCatalasePlant ExtractsSeleniumSuperoxide DismutaseIntrauterine growth retardation pigletMacleaya cordata extractNano-selenium

Identifiers

PMID34739675
OpenAlexW3208521511

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.