Evidence map›Paper›PMID 34739624›Full record

ArticleDigestive diseases and sciences2022

Validation of the New Diagnostic Criteria for Clinically Significant Portal Hypertension by Platelets and Elastography.

Kristian Podrug, Vladimir Trkulja, Marko Zelenika, Tomislav Bokun, Anita Madir, Tajana Filipec Kanizaj, James O'Beirne, Ivica Grgurevic

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Article in Digestive diseases and sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

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0cells of the map it votes in
8citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Kristian PodrugDepartment of Gastroenterology and Hepatology, University Hospital Split, Split, Croatia.
Vladimir TrkuljaDepartment of Pharmacology, University of Zagreb School of Medicine, Zagreb, Croatia.
Marko ZelenikaDepartment of Gastroenterology, Hepatology and Clinical Nutrition, University Hospital Dubrava, Av. Gojka Suska 6, 10 000, Zagreb, Croatia.
Tomislav BokunDepartment of Gastroenterology, Hepatology and Clinical Nutrition, University Hospital Dubrava, Av. Gojka Suska 6, 10 000, Zagreb, Croatia.
Anita MadirUniversity of Zagreb School of Medicine, Salata 3, 10 000, Zagreb, Croatia.
Tajana Filipec KanizajUniversity of Zagreb School of Medicine, Salata 3, 10 000, Zagreb, Croatia.
James O'BeirneSunshine Coast University Hospital, Sippy Downs, QLD, Australia.
Ivica GrgurevicDepartment of Gastroenterology, Hepatology and Clinical Nutrition, University Hospital Dubrava, Av. Gojka Suska 6, 10 000, Zagreb, Croatia. ivica.grgurevic@zg.htnet.hr.ORCID 0000-0003-0520-3483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsWe aimed to validate newly proposed noninvasive criteria for diagnosing clinically significant portal hypertension (CSPH) using liver stiffness measurements (LSM) by transient elastography (TE) and platelet count.

methodsDiagnostic performance of these new criteria for CSPH (LSM ≥ 25 kPa to rule in and Plt ≥ 150 × 10

resultsSeventy six (76) patients were included: 78.9% males, mean age 62 years, 36.8% suffered from alcoholic, 30.3% nonalcoholic fatty liver disease, 14.5% chronic viral hepatitis, 30.3% were obese, 52.6% had HVPG ≥ 10 mmHg, 56.6% had platelet count ≥ 150 × 10

conclusionBy using these simple noninvasive criteria 49/76 (64.5%) patients could be classified correctly for the presence/absence of CSPH, thus obviating the need for HVPG measurements.

Indexed as

Elasticity Imaging TechniquesHypertension, PortalBlood PlateletsFemaleHumansLiverLiver CirrhosisMaleMiddle AgedRetrospective StudiesChronic liver diseaseElastographyLiver cirrhosisPortal hypertension

Identifiers

PMID34739624
PMCPMC8569849

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.