ArticlePloS one2021
Exploring the distribution of grey and white matter brain volumes in extremely preterm children, using magnetic resonance imaging at term age and at 10 years of age.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Effect of enteral arachidonic acid and docosahexaenoic acid supplementation on brain volumes at term in preterm infants: a secondary outcome analysis of a randomised controlled trial.Archives of disease in childhood. Fetal and neonatal edition · 2026Article
- Brain volumes and cortical thickness and associations with cognition in children born extremely preterm.Pediatric research · 2025Article
- Brain volumes are related with motor skills at late childhood in children born extremely preterm.PloS one · 2025Article
- Language performance and brain volumes, asymmetry, and cortical thickness in children born extremely preterm.Pediatric research · 2024Article
- Machine Learning-Derived Active Sleep as an Early Predictor of White Matter Development in Preterm Infants.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Diagnostic performance of synthetic relaxometry for predicting neurodevelopmental outcomes in premature infants: a feasibility study.European radiology · 2023Article
- Disrupted resting-sate brain network dynamics in children born extremely preterm.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Emotional Regulation Interventions on Developmental Course for Preterm Children: A Systematic Review of Randomized Control Trials.Children (Basel, Switzerland) · 2023Review
- Extreme prematurity and perinatal risk factors related to extremely preterm birth are associated with complex patterns of regional brain volume alterations at 10 years of age: a voxel-based morphometry study.Frontiers in neurology · 2023Article
- Functional and Structural Brain Connectivity in Children With Bilateral Cerebral Palsy Compared to Age-Related Controls and in Response to Intensive Rapid-Reciprocal Leg Training.Frontiers in rehabilitation sciences · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate differences in brain volumes between children born extremely preterm and term born controls at term age and at 10 years of age. STUDY
designChildren born extremely preterm (EPT), up to 26 weeks and 6 days gestational age, in Stockholm between January 1 2004 to March 31 2007 were included in this population-based cohort study. A total of 45 EPT infants were included at term age and 51 EPT children were included at 10 years of age. There were 27 EPT children included at both time points. Two different control groups were recruited; 15 control infants were included at term age and 38 control children at 10 years of age. The primary outcomes were the grey and white matter volumes. Linear regression, adjusted for intracranial volume and sex, was used.
resultsAt term age, the extremely preterm infants had significantly smaller grey matter volume compared to the control infants with an adjusted mean difference of 5.0 cm3 and a 95% confidence interval of -8.4 to -1.5 (p = 0.004). At 10 years of age the extremely preterm children had significantly smaller white matter volume compared to the control children with an adjusted mean difference of 6.0 cm3 and a 95% confidence interval of -10.9 to -1.0 (p = 0.010).
conclusionExtremely preterm birth was associated with reduced grey matter volume at term age and reduced white matter volume at 10 years of age compared to term born controls.
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